Results 51 to 60 of about 430,629 (299)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Impact of web accessibility on cognitive engagement in individuals without disabilities: Evidence from a psychophysiological study.

open access: yesPLoS ONE
Web accessibility features on websites are designed for individuals with disabilities that include low vision and cognitive impairments, but such features can benefit everyone.
Merve Ekin   +5 more
doaj   +1 more source

Towards Designing a Set of Usability and Accessibility Heuristics Focused on Cognitive Diversity: An Exploratory Case Study with Generative Artificial Intelligence

open access: yesInformation
This paper discusses the design and evaluation of a set of heuristics (U + A) to assess the usability and accessibility of interactive systems in terms of cognitive diversity in an integrated way.
Afra Pascual Almenara   +1 more
doaj   +1 more source

Designing the journey for inclusivity and accessibility in virtual manufacturing environments: An exploration through empathy [PDF]

open access: yesMATEC Web of Conferences
With one in four EU adults having disabilities and only half employed full-time, there is a need for enhanced workforce inclusion and accessibility.
Grech Amy   +4 more
doaj   +1 more source

Brain-Machine Interfaces to Assist the Blind

open access: yesFrontiers in Human Neuroscience, 2021
The loss or absence of vision is probably one of the most incapacitating events that can befall a human being. The importance of vision for humans is also reflected in brain anatomy as approximately one third of the human brain is devoted to vision.
Maurice Ptito   +9 more
doaj   +1 more source

The roles of motivation and ability in controlling the consequences of stereotype suppression [PDF]

open access: yes, 2000
Two experiments investigated the conditions under which previously suppressed stereotypes are applied in impression formation. In Experiment 1, the extent to which a previously suppressed racial stereotype influenced subsequent impressions depended on ...
Bargh, J. A.   +13 more
core   +2 more sources

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

How Well Do Ontario Library Web Sites Meet New Accessibility Requirements? [PDF]

open access: yes, 2012
New changes to Ontario law will require library web sites to comply with the Web Content Accessibility Guidelines, version 2.0 (WCAG 2.0). This study evaluates 64 Ontario university, college, and public library web sites to see how well they comply with ...
Oud, Joanne
core   +3 more sources

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Local Government Website Accessibility—Evidence from Poland

open access: yesAdministrative Sciences, 2020
The paper investigates the accessibility of local government websites. It focuses in particular on disability, e-administration, and web accessibility standards for the visually impaired.
Karol Król, Dariusz Zdonek
doaj   +1 more source

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