Results 61 to 70 of about 430,629 (299)

Full-body motion-based game interaction for older adults [PDF]

, 2012
Older adults in nursing homes often lead sedentary lifestyles, which reduces their life expectancy. Full-body motion-control games provide an opportunity for these adults to remain active and engaged; these games are not designed with age-related ...
Gerling, Kathrin M., Livingston, Ian J., Mandryk, Regan L., Nacke, Lennart E.   +3 more
core   +3 more sources

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Museums as disseminators of niche knowledge: Universality in accessibility for all [PDF]

, 2019
Accessibility has faced several challenges within audiovisual translation Studies and gained great opportunities for its establishment as a methodologically and theoretically well-founded discipline. Initially conceived as a set of services and practices
Rizzo A
core   +2 more sources

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Expectation Violation Influences Neural Responses to the Accessibility of Cognitions Related to Suicide and Life: A Simultaneous EEG-fNIRS Study

Brain Sciences
Background/Objectives: Increased accessibility of suicidal cognitions reflects the cognitive processes underlying the acquisition of suicidal thoughts. Previous research shows that expectation violation reduces the accessibility of life cognitions rather
Bo Liu, Yuntena Wu, Tonglin Jin, Zeyu Lei   +3 more
doaj   +1 more source

Accessibility of Cypriot University websites in Cyprus [PDF]

, 2011
: Access and equity in higher education is a complicated discipline related to social, economical, technological and political developments in a country.
Mavrou, Katerina, Michailidou, Eleni, Zaphiris, Panayiotis   +2 more
core   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

The Needs of People with Developmental Disabilities Vis-à-Vis Accessibility Standards in the Built Environment

Buildings
People with developmental disabilities, who represent about 2% of the global population, encounter diverse functional and cognitive challenges that adversely impact their navigation and accessibility experiences in the built environments.
Samir E. Chidiac, Mouna A. Reda
doaj   +1 more source

Information structure and the accessibility of clausally introduced referents [PDF]

, 2013
This paper will examine the role of various factors in affecting the salience, and hence the accessibility to pronominal reference, of entities introduced into a discourse by a full clause.
Borthen, Kaja, Gundel, Jeanette K., Hegarty, Michael   +2 more
core