Results 61 to 70 of about 350,055 (312)

Sleep deprivation impairs cognitive performance, alters task-associated cerebral blood flow and decreases cortical neurovascular coupling-related hemodynamic responses

Scientific Reports, 2021
Sleep deprivation (SD) is a common condition and an important health concern. In addition to metabolic and cardiovascular risks, SD associates with decreases in cognitive performance.
Tamas Csipo, Agnes Lipecz, Cameron Owens, Peter Mukli, Jonathan W. Perry, Stefano Tarantini, Priya Balasubramanian, Ádám Nyúl-Tóth, Valeriya Yabluchanska, Farzaneh A. Sorond, J. Mikhail Kellawan, György Purebl, William E. Sonntag, Anna Csiszar, Zoltan Ungvari, Andriy Yabluchanskiy   +15 more
doaj   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Driving into the sunset: Supporting cognitive functioning in older drivers [PDF]

, 2011
Copyright @ 2011 Mark S. Young and David Bunce - This article has been made available through the Brunel Open Access Publishing Fund.The rise in the aging driver population presents society with a significant challenge-how to maintain safety and mobility
Mark S. Young, Young, Mark S., Bunce, David, Young, MS, David Bunce, Bunce, D   +5 more
core   +1 more source

Predicting episodic memory performance using different biomarkers: results from Argentina-Alzheimer’s Disease Neuroimaging Initiative

Neuropsychiatric Disease and Treatment, 2016
María Julieta Russo,1 Gabriela Cohen,1 Patricio Chrem Mendez,1 Jorge Campos,1 Federico E Nahas,1 Ezequiel I Surace,1 Silvia Vazquez,1 Deborah Gustafson,2,3 Salvador Guinjoan,1 Ricardo F Allegri,1 Gustavo Sevlever1 On behalf of the Argentina ...
Russo MJ, Cohen G, Mendez P, Campos J, Nahas FE, Surace E, Vazquez S, Gustafson D, Guinjoan S, Allegri R, Sevlever G   +10 more
doaj  

The cost of monitoring in time-based prospective memory

Scientific Reports
Time-based prospective memory (TBPM) involves remembering to perform actions at specific times in the future. Several studies suggest that monetary consequences improve prospective remembering; however, the effect of monetary consequences on strategic ...
Gianvito Laera, Jasmin Brummer, Alexandra Hering, Matthias Kliegel, Sebastian Horn   +4 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Elderly Women Empowerment in the Aging Process: A Cognitive Perspective

, 2022
This study was carried out to draw a road map for the cognitive empowerment of women in the aging process. The fact that women are under negative effects in physical, biological, and cultural contexts reveals the fact that they may have some ...
Özsungur, Fahri
core   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Age related cognitive impairments and assistive web-base technology [PDF]

, 2008
Several researchers argue that age related cognitive impairments have detrimental affect on use of web services by older adults. However little and systematic applied research has been conducted on how age related cognitive impairments might affect the ...
Money, A, Lines, L, Elliman, T
core  

Long-Term DL-3-n-Butylphthalide Treatment Alleviates Cognitive Impairment Correlate With Improving Synaptic Plasticity in SAMP8 Mice

Frontiers in Aging Neuroscience, 2018
Alzheimer’s disease (AD) is the most prevalent form of dementia worldwide. AD is characterized by mild cognitive impairment at onset, irreversibly progressing with age to severe neurodegeneration and cognitive deficits in the late stages.
Chaonan Lv, Chaonan Lv, Qinying Ma, Qinying Ma, Bing Han, Bing Han, Jing Li, Jing Li, Yuan Geng, Yuan Geng, Xiaoman Zhang, Xiaoman Zhang, Mingwei Wang, Mingwei Wang   +13 more
doaj   +1 more source