Results 51 to 60 of about 7,842,313 (297)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Mediators of Change in Cognitive Behavior Therapy for Clinical Burnout

, 2019
Evidence supporting the effectiveness of cognitive behavior therapy (CBT) for stress-related illness is growing, but little is known about its mechanisms of change.
Salomonsson, Sigrid,, Santoft, F,, Kecklund, G, Kecklund, Goran,, Ljotsson, Brjann,, Hesser, H, Hedman-Lagerlof, Erik,, Hedman-Lagerlof, E, Santoft, Fredrik,, Ost, Lars-Goran,, Hesser, Hugo,, Ost, L-G, Ljotsson, B, Lindsater, Elin,, Lekander, Mats,, Lekander, M,, Lindsater, E, Salomonsson, S,   +17 more
core   +1 more source

Cognitive behavior therapy in panic disorder and comorbid major depression - A naturalistic study [PDF]

, 2000
Background: There is a lack of evidence about the effectiveness of cognitive behavior therapies (CBT) in settings of routine clinical care as well as in the treatment of panic and comorbid disorders. Methods: We investigated a group-oriented CBT approach
Fichter, Manfred M., Trenkamp, Susanne, Rief, Winfried, Auer, Claudia   +3 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Acceptance and utilization of web-based self-help for caregivers of children with externalizing disorders

Child and Adolescent Psychiatry and Mental Health
Background Web-based self-help interventions for parents of children with ADHD and other externalizing disorders have been proven to be effective. In order to recommend individualized and optimized interventions, a better understanding of the acceptance ...
Laura Wähnke, Julia Plück, Mikel Bodden, Angela Ernst, Marie-Theres Klemp, Judith Mühlenmeister, Manfred Döpfner   +6 more
doaj   +1 more source

The importance of familial risk factors in children with ADHD: direct and indirect effects of family adversity, parental psychopathology and parenting practices on externalizing symptoms

Child and Adolescent Psychiatry and Mental Health, 2022
Background Children experiencing unfavorable family circumstances have an increased risk of developing externalizing symptoms. The present study examines the direct, indirect and total effects of family adversity, parental psychopathology, and positive ...
Lea Teresa Jendreizik, Christopher Hautmann, Elena von Wirth, Christina Dose, Ann-Kathrin Thöne, Anne-Katrin Treier, Tobias Banaschewski, Katja Becker, Daniel Brandeis, Julia Geissler, Johannes Hebebrand, Sarah Hohmann, Martin Holtmann, Michael Huss, Thomas Jans, Anna Kaiser, Sabina Millenet, Luise Poustka, Priska Schneider, Manfred Döpfner   +19 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Psychosocial characteristics and daily impairment in women with persistent perinatal depressive symptoms: A large-scale cohort study

Journal of Affective Disorders Reports
Background: This study aimed to determine the prevalence of persistent perinatal depressive symptoms and to identify the psychosocial characteristics associated with persistent symptoms among Japanese women.
Haruna Irino, Satoko Sasagawa, Chika Yokoyama, Aiko Okatsu, Ayako Kanie, Chika Kubota, Yasue Mitamura, Sayaka Aoyama, Miyuki Makino, Aiichiro Nakajima, Yaeko Kataoka, Masaru Horikoshi, Hironori Kuga, Masaya Ito   +13 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Cognitive behavior therapy and dialectical behavior therapy for treating obese emotional eaters

, 2012
This study describes the treatment of obese individuals who rated high on emotional eating using four case studies that involved 22 sessions of either cognitive behavioral therapy (CBT) or dialectical behavioral therapy (DBT).
Strodl, Esben, Glisenti, Kevin
core   +1 more source