Results 61 to 70 of about 7,842,313 (297)

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Estructura Factorial Preliminar de la Escala de Creencias de Mujeres de O´Kelly en Población Mexicana

Avances en Psicología Latinoamericana, 2011
La versión mexicana de la australiana o’Kelly Women’s Belief scales fue administrada a una muestra de 363 mujeres nacidas y residentes en México. el análisis factorial con rotación varimax y con autovalor de 3 mostró 36 reactivos de los 92 originales en ...
Arturo Heman Contreras, Leonor Lega, Margarita Villaseñor Ponce, Ana Paulina Alva Jimenez, Lorena Garcia Guerrero   +4 more
doaj  

Psychological treatments for mental health symptoms associated with COVID‐19 infection: A scoping review

PCN Reports
The aim of this scoping review was to synthesize published studies and ongoing clinical trials of psychological interventions for mental health problems associated with COVID‐19 infection.
So Sugita, Kotone Hata, Krandhasi Kodaiarasu, Naoki Takamatsu, Kentaro Kimura, Christian Miller, Lecsy Gonzalez, Ikue Umemoto, Keitaro Murayama, Tomohiro Nakao, Shinsuke Kito, Masaya Ito, Hironori Kuga   +12 more
doaj   +1 more source

The adaptation of cognitive behavioural therapy for adult Maori clients with depression: A pilot study [PDF]

, 2008
A semistructured cognitive behavioural therapy (CBT) programme for depression was adapted for use with Maori adult clients with depression. Adaptations were developed in consultation with an advisory group consisting of Maori clinical psychologists and ...
Bennett, Simon T., Babbage, Duncan R., Flett, Ross A.   +2 more
core  

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Exposure to traumatic events, PTSD, and alcohol use: A comparative study in Japan by type of traumatic event and gender

PCN Reports
Aim The association between alcohol use disorder (AUD) and posttraumatic stress disorder (PTSD) is well established. However, many studies in Japan have focused on trauma related to natural disasters, which differ from international studies that include ...
Yuriko Takagishi, Masaya Ito, Hironori Kuga, Masaru Horikoshi   +3 more
doaj   +1 more source

A Theoretical Review of Rational Emotive Behavior Therapy (REBT) and Unconditional Self-Acceptance for Alleviating Maladaptive Perfectionism

This study aimed to examine the theoretical foundations and counseling implications of Unconditional Self-Acceptance (USA), a core concept of Rational Emotive Behavior Ther apy (REBT), for alleviating maladaptive perfectionism through a literature ...
Seung-Mi Choi, Korean Association of Rational Emotive and Cognitive Behavior Therapy, Hyun Jeong Kim   +2 more
core   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Maladaptive cognitive processes during exposure in people with OCD (checking subtype) [PDF]

, 2007
Cognitive Behaviour Therapy (CBT) is regarded as one of the most efficacious psychological treatments of Obsessive Compulsive Disorder (OCD) and is recommended in the recent National Institute for Clinical Excellence guidelines (NICE, 2006). Despite this,
Robson, Stacey
core   +4 more sources

Application of the Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in a Group Format for Adults: A Scoping Review Protocol

Behavioral Sciences
The group format of the Unified Protocol for Transdiagnostic Treatment of Emotional Disorders (UP) shows promise as a efficient method for delivering established and effective psychological treatments for emotional disorders.
Machiko Kajiwara, Noriko Kato, Motohiro Nishiuchi, Hiroko Fujisato, Kyousuke Kaneko, Hironori Kuga, Masaya Ito   +6 more
doaj   +1 more source