Results 81 to 90 of about 254,711 (292)

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani, Lakshmi Pillai, Reid D. Landes, Aliyah Glover, Shannon Doerhoff, Jennifer Kleiner, Mitesh Lotia, Rohit Dhall, Edgar Garcia‐Rill   +8 more
wiley   +1 more source

Attention bias dynamics and symptom severity during and following CBT for social anxiety disorder [PDF]

, 2016
Objective: Threat-related attention bias figures prominently in contemporary accounts of the maintenance of anxiety disorders, yet longitudinal intervention research relating attention bias to anxiety symptom severity is limited.
Beevers, CG, Bernstein, A, Davis, ML, Koster, Ernst, Reinecke, A, Rosenfield, D, Smits, JAJ, Zvielli, A   +7 more
core   +2 more sources

Predicting Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex Using a Fusion Model Integrating Lesion Network Mapping and Machine Learning

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu, Qi Wang, Suhui Kuang, Dezhi Cao, Ping Ding, Shaohui Zhang, Haihua Wei, Zhirong Wei, Jinshan Xu, Xinyu Huang, Bing Liu, Shuli Liang   +11 more
wiley   +1 more source

An evolved cognitive bias for social norms [PDF]

, 2007
Social norms are a widely used concept for explaining human behavior, but there are few studies exploring how we cognitively utilize them. We incorporate here an evolutionary approach to studying social norms, predicting that if norms have been critical ...
Miller, Ralph R, O'Gorman, Rick, Wilson, David Sloan   +2 more
core   +1 more source

Cognitive Status in People With Epilepsy in the Republic of Guinea: A Prospective, Case–Control Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective People with epilepsy (PWE) may experience cognitive deficits but fail to undergo formal evaluation. This study compares cognitive status between PWE and healthy controls in the West African Republic of Guinea. Methods A cross‐sectional, case–control study was conducted in sequential recruitment phases (July 2024–July 2025) at Ignace ...
Maya L. Mastick, Cheick O. Soumah, Malé Doré, Oumar Mara, Desiré Neldje, Fodé A. Cissé, Toure M. Lamine, Aminata Diallo, Seungwon Lee, Siddharth Satish, Alexander J. X. Chen, Alice Liu, Nomin Enkhtsetseg, Farrah J. Mateen, The Guinea Epilepsy Project   +14 more
wiley   +1 more source

Machine learning meta-analysis identifies individual characteristics moderating cognitive intervention efficacy for anxiety and depression symptoms

npj Digital Medicine
Cognitive training is a promising intervention for psychological distress; however, its effectiveness has yielded inconsistent outcomes across studies. This research is a pre-registered individual-level meta-analysis to identify factors contributing to ...
Thalia Richter, Reut Shani, Shachaf Tal, Nazanin Derakshan, Noga Cohen, Philip M. Enock, Richard J. McNally, Nilly Mor, Shimrit Daches, Alishia D. Williams, Jenny Yiend, Per Carlbring, Jennie M. Kuckertz, Wenhui Yang, Andrea Reinecke, Christopher G. Beevers, Brian E. Bunnell, Ernst H. W. Koster, Sigal Zilcha-Mano, Hadas Okon-Singer   +19 more
doaj   +1 more source

Statistical competencies for medical research learners: What is fundamental? [PDF]

, 2017
IntroductionIt is increasingly essential for medical researchers to be literate in statistics, but the requisite degree of literacy is not the same for every statistical competency in translational research.
Benn, Emma KT, Carter, Rickey E, Enders, Felicity T, Grambow, Steven C, Kidwell, Kelley M, Larson, Joseph, Lindsell, Christopher J, Mayo, Matthew S, Oster, Robert A, Perkins, Susan M, Pollock, Brad H, Rahbar, Mohammad H, Spratt, Heidi, Thurston, Sally W, Welty, Leah J   +14 more
core   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

The positivity effect in older adults : the role of affective interference and inhibition [PDF]

, 2010
Objectives: Research shows that aging often involves a decrease in the experience of negative affect and might even be associated with a stabilization or an increase in experience concerning positive affect.
De Raedt, Rudi, Dierckx, Eva, Goeleven, Ellen   +2 more
core   +2 more sources

Patterns of Postictal Abnormalities in Relation to Status Epilepticus in Adults

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Abnormalities on peri‐ictal diffusion‐weighted magnetic resonance imaging (DWI‐PMAs) are well‐established for patients with status epilepticus (SE), but knowledge on patterns of DWI‐PMAs and their prognostic impact is sparse. Methods This systematic review and individual participant data meta‐analysis included observational studies ...
Andrea Enerstad Bolle, Silvana Sarria‐Estrada, Thomas Bonduelle, Bertram Daniel Dynesen, Manuel Toledo, Zhu Chung Che, Kjell Heuser, Anastasios Chatzikonstantinou, Jérôme Aupy, Udaya Seneviratne, Estevo Santamarina Perez, Christoph Patrick Beier   +11 more
wiley   +1 more source