ABSTRACT Background Apolipoprotein ε4 (APOE ε4) is a potent genetic risk factor for Alzheimer's disease (AD). However, its role in cerebral small vessel disease (CSVD) remains unclear. Given the clinical and pathological similarities between CSVD and AD, this study aimed to investigate the associations of APOE ε4 gene dosage with cognitive function and
Tingru Jin +6 more
wiley +1 more source
Cognitive Biases and Gender Opposition: Analysis from the Perspective of the Individual, Community, Society and Platforms [PDF]
Social media makes it possible for the public to communicate and share conceptions. As a hot online topic, gender discourse has received huge attention and discussion from different users.
Gao Hanxi
doaj +1 more source
Interliminal design: Mitigating cognitive bias and design distortion [PDF]
The presence of cognitive biases and heuristics induces design distortions, unintended mismatches between desired and actual design outcomes. Interliminal Design is an intentional, adaptive and imaginative design process that mitigates design distortions.
Denmark, Deaunne +2 more
core
The Relationship Between Inflammation and Central Nervous System in Multiple Sclerosis
ABSTRACT Aim Multiple sclerosis is an autoimmune demyelination disease that is seen especially in the young population and has a progressive course, causing motor, sensory, and cognitive deficits. In the literature, the pathogenesis of MS disease and the interconnection between the immune and central nervous system in the disease have not been fully ...
Gamze Ansen +5 more
wiley +1 more source
Network Localization of Fatigue in Multiple Sclerosis
ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo +12 more
wiley +1 more source
Aim and Background: Psychotic-like experiences are considered non-clinical and mild forms of psychotic disorders that are associated with negative consequences such as distress, mental disorders and functional impairments.
Dorna nabizadeh asl +3 more
doaj
The development of national prejudice, in-group favouritism and self-stereotypes in British children [PDF]
This study explores the development of national prejudice, ingroup favouritism and self-stereotyping in a sample of 329 British children. The aim was to test the prediction, derived from self-categorization theory (Oakes, Haslam & Turner, 1994; Spears ...
Rutland, Adam
core +1 more source
Use of Symptomatic Drug Treatment for Fatigue in Multiple Sclerosis and Patterns of Work Loss
ABSTRACT Objective To describe the use of central stimulants and amantadine for fatigue in MS and evaluate a potential association with reduced work loss in people with MS. Methods We conducted a nationwide, matched, register‐based cohort study in Sweden (2006 to 2023) using national registers with prospective data collection.
Simon Englund +3 more
wiley +1 more source
An architecturally constrained model of random number generation and its application to modeling the effect of generation rate [PDF]
Random number generation (RNG) is a complex cognitive task for human subjects, requiring deliberative control to avoid production of habitual, stereotyped sequences. Under various manipulations (e.g., speeded responding, transcranial magnetic stimulation,
Anderson +42 more
core +2 more sources
Acoustic Measures Capture Speech Dysfunction in Spinocerebellar Ataxia
ABSTRACT Objective Spinocerebellar ataxias (SCA) are hereditary cerebellar degenerative disorders with a common feature of dysarthria, involving impaired phonatory and articulatory control of speech, thereby affecting social communication. In this study, we investigated whether acoustic measures could objectively measure speech dysfunction and identify
Zena Fadel +5 more
wiley +1 more source

