Results 181 to 190 of about 361,832 (264)

Restriction of Individual Branched‐Chain Amino Acids has Distinct Effects on the Development and Progression of Alzheimer's Disease in 3xTg Mice

Advanced Science, EarlyView.
Protein restriction (PR) slows Alzheimer's disease (AD) in mice, and other benefits of PR are due to decreased branched‐chain amino acids (BCAAs). We show that restricting any BCAA has benefits, with sex‐ and BCAA‐specific impacts on pathology, molecular signaling, and cognition.
Reji Babygirija, Cara L. Green, Michelle M. Sonsalla, Izabelle Marie F. Le, Fan Xiao, Sarah Yandell, Mariah F. Calubag, Michaela E. Trautman, Anna Tobon, Ryan Matoska, Chung‐Yang Yeh, Charles I. Opara, Isaac Grunow, Diana Vertein, Sophia Schlorf, Bailey A. Knopf, Michael J. Rigby, David A. Harris, Mark P. Keller, Alan D. Attie, Luigi Puglielli, Cholsoon Jang, Dudley W. Lamming   +22 more
wiley   +1 more source

Ultrasound Modulation of Visual Circuits in Mice Independent of Auditory Confound

Advanced Science, EarlyView.
In this study, Qiu et al. found that low‐intensity ultrasound can directly activate sparse ultrasound‐sensitive neurons (UNs) in the primary visual cortex (V1) of deafened mice. The proportion of these sparse UNs is pressure‐dependent. Furthermore, ultrasound modulates visual circuitry with distinct excitatory and inhibitory effects.
Jiaru He, Jiejun Zhu, Xinxin Wang, Zihao Chen, Jin Yang, Zhen Yuan, Hongzhi Xu, Lei Sun, Zhihai Qiu   +8 more
wiley   +1 more source

Longitudinal associations of psychological distress with subsequent cognitive decline and dementia: a multi-cohort study. [PDF]

Alzheimers Dement
Stafford J, Dekhtyar S, Russ TC, Singh-Manoux A, Maddock J, Walters K, Orgeta V, Davies N, Kirkbride JB, Richards M, Howard R, Patalay P.   +11 more
europepmc   +1 more source

The Impact of Air Pollution and Obesity on Cognitive Decline and Risk of Alzheimer's Disease. [PDF]

Int J Mol Sci
Keller ZA, Eggers KM, Nixon JP, Butterick TA.   +3 more
europepmc   +1 more source

Associations of anticholinergic burden of medication with cognitive decline and longitudinal brain atrophy in the Alzheimer's disease spectrum. [PDF]

Front Aging Neurosci
Teipel S, Grazia A, Peters O, Priller J, Schneider A, Wiltfang J, Bartels C, Schott BH, Jessen F, Duezel E, Yakupov R, Buerger K, Perneczky R, Laske C, Spottke A, Wagner M, Peltner J, Kilimann I, Haenisch B.   +18 more
europepmc   +1 more source