Results 181 to 190 of about 335,081 (290)

Social Networks, Social Integration, and Social Engagement Determine Cognitive Decline in Community-Dwelling Spanish Older Adults [PDF]

, 2003
Marı́a Victoria Zunzunegui, Beatriz Alvarado, Teodoro del Ser, À. Otero   +3 more
openalex   +1 more source

Nucleotides as an Anti‐Aging Supplementation in Older Adults: A Randomized Controlled Trial (TALENTs study)

Advanced Science, EarlyView.
The TALENTs randomized controlled trial evaluates the potential of nucleotides supplementation as an anti‐aging intervention in older adults. After 19 weeks, nucleotides supplementation significantly reduces DNA methylation age, suggesting a delay in epigenetic aging, and improves insulin sensitivity without severe adverse events.
Shuyue Wang, Lixia Song, Rui Fan, Qianqian Chen, Ruisheng Fu, Mei You, Yuxiao Wu, Meng Cai, Yong Li, Meihong Xu   +9 more
wiley   +1 more source

Amyloid accumulation, brain atrophy, and cognitive decline in emergent Alzheimer's disease. [PDF]

Alzheimers Dement (Amst)
Xia Y, Bourgeat P, Doré V, Fripp J, Lim YY, Laws SM, Fowler C, Rowe CC, Masters CL, Coulson EJ, Maruff P, AIBL Research Group.   +11 more
europepmc   +1 more source

Apolipoprotein 4 Allele Status, Depressive Symptoms, and Cognitive Decline in Middle-Aged and Elderly Persons Without Dementia [PDF]

, 2003
Helen Lavretsky
openalex   +1 more source

Dysfunctional Decidual CD4+T Cells Induce Recurrent Pregnancy Loss via Palmitoylation‐Dependent Tim‐3 Lysosomal Sorting and Degradation

Advanced Science, EarlyView.
Dysfunctional decidual CD4+T cells induce recurrent pregnancy loss via palmitoylation‐dependent Tim‐3 lysosomal sorting and degradation. The integrated bioinformatics, proteomic, functional and model studies elucidate that Tim‐3 is palmitoylated by ZDHHC3 at Cys9. Sortilin bound to and directed palmitoylated Tim‐3 toward lysosome degradation, resulting
Liyuan Cui, Xinhang Meng, Yujie Luo, Jinfeng Qian, Fengrun Sun, Mingke Qiu, Songcun Wang   +6 more
wiley   +1 more source

The Role of Childhood Adversity and Social Drivers of Health in Subjective Cognitive Decline. [PDF]

Prev Chronic Dis
Joshi A, Yeo J.
europepmc   +1 more source

Declining brain activity in cognitively normal apolipoprotein E ɛ4 heterozygotes: A foundation for using positron emission tomography to efficiently test treatments to prevent Alzheimer's disease

, 2001
Eric M. Reiman, Richard J. Caselli, Kewei Chen, Gene E. Alexander, Daniel Bandy, Jennifer Frost   +5 more
openalex   +1 more source

Reliable Change Indexes for Memory Performance in Schizophrenia as a Means to Determine Drug-Induced Cognitive Decline [PDF]

, 2003
Steffen Moritz, Grant L. Iverson, Todd S. Woodward   +2 more
openalex   +1 more source

Gompertz Law‐Based Biological Age (GOLD BioAge): A Simple and Practical Measurement of Biological Ageing to Capture Morbidity and Mortality Risks

Advanced Science, EarlyView.
The Gompertz law‐based biological age metric (GOLD BioAge) introduces interpretable convenient and interpretable calculations to capture mortality, disease, and frailty risks. Its applications to proteomics and metabolomics (ProtAge and MetAge) demonstrate clinical potential to enhance aging evaluation and prevent age‐related diseases.
Meng Hao, Hui Zhang, Jingyi Wu, Yaqi Huang, Xiangnan Li, Meijia Wang, Shuming Wang, Jiaofeng Wang, Jie Chen, Zhi jun Bao, Li Jin, Xiaofeng Wang, Zixin Hu, Shuai Jiang, Yi Li   +14 more
wiley   +1 more source

Visual processing capacity and cognitive decline in Parkinson's disease. [PDF]

BMJ Neurol Open
Gerner K, Bublak P, Finke K, Schrenk S, Ruiz-Rizzo AL, Wagner F, Klingner C, Brodoehl S.   +7 more
europepmc   +1 more source