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Postoperative cognitive decline
Journal of Anesthesia, 2009Memory loss and lack of concentration are symptoms that frequently occur in patients who have undergone a surgical procedure. Although cognitive function can be assessed using neuropsychological tests, reliable diagnosis of postoperative cognitive decline (POCD) appears to be difficult. Therefore, the true incidence of POCD is unknown.
Anne-Mette, Sauër +2 more
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Diabetes and cognitive decline
2022Epidemiologic studies have documented an association between diabetes and increased risk of cognitive decline in the elderly. Based on animal model studies, several mechanisms have been proposed to explain such an association, including central insulin signaling, neurodegeneration, brain amyloidosis, and neuroinflammation.
Bellia, Chiara +5 more
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Clinics in Geriatric Medicine, 1992
Many studies of age-related cognitive decline have failed to distinguish between usual and successful aging. Although some degree of cognitive impairment is associated with aging, when one looks at average performance, there is great variability among individuals, with many showing little or no deleterious effects of aging on intellectual abilities ...
K A, Nolan, J P, Blass
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Many studies of age-related cognitive decline have failed to distinguish between usual and successful aging. Although some degree of cognitive impairment is associated with aging, when one looks at average performance, there is great variability among individuals, with many showing little or no deleterious effects of aging on intellectual abilities ...
K A, Nolan, J P, Blass
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The Journals of Gerontology: Series B, 2022
AbstractObjectivesSubjective cognitive decline (SCD) is a known risk factor for Alzheimer’s disease. However, little research has examined whether healthy older adults with SCD (SCD+) exhibit lower cognition and increased rates of cognitive decline compared to those without SCD (SCD−). The goal of this study was to examine if cognitive change over a 15-
Cassandra Morrison, Michael D Oliver
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AbstractObjectivesSubjective cognitive decline (SCD) is a known risk factor for Alzheimer’s disease. However, little research has examined whether healthy older adults with SCD (SCD+) exhibit lower cognition and increased rates of cognitive decline compared to those without SCD (SCD−). The goal of this study was to examine if cognitive change over a 15-
Cassandra Morrison, Michael D Oliver
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JAMA, 2015
Stroke and cognitive impairment are common among older persons.1 It is estimated that the lifetime risk for stroke is approximately 1 in 5 for women and 1 in 6 for men,2 and almost one-third of persons with stroke, which typically may involve motor, sensory, or other deficits, may have a significant degree of cognitive impairment within several months ...
Philip B, Gorelick, David, Nyenhuis
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Stroke and cognitive impairment are common among older persons.1 It is estimated that the lifetime risk for stroke is approximately 1 in 5 for women and 1 in 6 for men,2 and almost one-third of persons with stroke, which typically may involve motor, sensory, or other deficits, may have a significant degree of cognitive impairment within several months ...
Philip B, Gorelick, David, Nyenhuis
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Response to Hypoxia in Cognitive Decline
Rejuvenation Research, 2021Inflammaging, the increase of proinflammatory processes with increasing age, has multiple mechanisms from increasing numbers of senescent cells secreting cytokines to changes in metabolic processes. Alterations of oxygen metabolism with aging, especially decreased levels of O 2 with age ...
James W, Larrick +2 more
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[Cognitive decline and hypertension].
Archives des maladies du coeur et des vaisseaux, 2003The prevalence and incidence of degenerative and vascular dementia increase exponentially with age. Several studies in recent years have implicated hypertension as a risk factor not only for vascular dementia but also for degenerative dementia such as Alzheimer's disease.
Rigaud, A.S. +7 more
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Nursing Older People, 2012
There is growing consensus that dementia has a long gestation period; it is known that neurofibrillary tangles and amyloid plaques, the hallmarks of pathological change in dementia, are present in the brains of young adults. This study aimed to examine if decline in cognitive function can be detected earlier than previously thought.
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There is growing consensus that dementia has a long gestation period; it is known that neurofibrillary tangles and amyloid plaques, the hallmarks of pathological change in dementia, are present in the brains of young adults. This study aimed to examine if decline in cognitive function can be detected earlier than previously thought.
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Phosphodiesterase Inhibition in Cognitive Decline
Journal of Alzheimer's Disease, 2014Understanding the cellular and molecular processes involved in learning and memory will help in the development of safe and effective cognitive enhancers. The cAMP response element-binding (CREB) may be a universal modulator of processes required for memory formation, and increasing the levels of second messengers like cAMP and cGMP could ultimately ...
Carolina, García-Barroso +8 more
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Homocysteine, estrogen and cognitive decline
Climacteric, 2006Factors that contribute to cognitive decline in women from midlife remain poorly understood. There are circumstantial data indicating a positive association between homocysteine and cognitive decline and that endogenous and exogenous estrogen may influence homocysteine levels.
S, Shah, R J, Bell, S R, Davis
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