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The Journals of Gerontology: Series B, 2022
AbstractObjectivesSubjective cognitive decline (SCD) is a known risk factor for Alzheimer’s disease. However, little research has examined whether healthy older adults with SCD (SCD+) exhibit lower cognition and increased rates of cognitive decline compared to those without SCD (SCD−). The goal of this study was to examine if cognitive change over a 15-
Cassandra Morrison, Michael D Oliver
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AbstractObjectivesSubjective cognitive decline (SCD) is a known risk factor for Alzheimer’s disease. However, little research has examined whether healthy older adults with SCD (SCD+) exhibit lower cognition and increased rates of cognitive decline compared to those without SCD (SCD−). The goal of this study was to examine if cognitive change over a 15-
Cassandra Morrison, Michael D Oliver
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Clinics in Geriatric Medicine, 1992
Many studies of age-related cognitive decline have failed to distinguish between usual and successful aging. Although some degree of cognitive impairment is associated with aging, when one looks at average performance, there is great variability among individuals, with many showing little or no deleterious effects of aging on intellectual abilities ...
K A, Nolan, J P, Blass
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Many studies of age-related cognitive decline have failed to distinguish between usual and successful aging. Although some degree of cognitive impairment is associated with aging, when one looks at average performance, there is great variability among individuals, with many showing little or no deleterious effects of aging on intellectual abilities ...
K A, Nolan, J P, Blass
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[Cognitive decline and hypertension].
Archives des maladies du coeur et des vaisseaux, 2003The prevalence and incidence of degenerative and vascular dementia increase exponentially with age. Several studies in recent years have implicated hypertension as a risk factor not only for vascular dementia but also for degenerative dementia such as Alzheimer's disease.
Rigaud, A.S. +7 more
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Nursing Older People, 2012
There is growing consensus that dementia has a long gestation period; it is known that neurofibrillary tangles and amyloid plaques, the hallmarks of pathological change in dementia, are present in the brains of young adults. This study aimed to examine if decline in cognitive function can be detected earlier than previously thought.
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There is growing consensus that dementia has a long gestation period; it is known that neurofibrillary tangles and amyloid plaques, the hallmarks of pathological change in dementia, are present in the brains of young adults. This study aimed to examine if decline in cognitive function can be detected earlier than previously thought.
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This entry provides a comprehensive overview of Subjective Cognitive Decline (SCD), emphasizing its significance as an early marker in the continuum of physiological cognitive aging and neurodegenerative diseases—such as Mild Cognitive Impairment (MCI) and Alzheimer’s Disease (AD).
Marina Maffoni, Annalisa Magnani
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Marina Maffoni, Annalisa Magnani
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Terminal decline in cognitive function
Neurology, 2003Impending death is thought to be associated with age-related cognitive decline, but this association has not been well studied.Participants were 763 older Roman Catholic nuns, priests, and brothers without dementia at baseline. They completed an average of 5.6 annual evaluations (range 2 to 9), with >95% follow-up participation in survivors.
R S, Wilson +4 more
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Cognitive decline in heart failure
Heart Failure Reviews, 2016Cognitive impairment (CI) is common in older adults with heart failure (HF). The prevalence of CI is higher among patients with HF than in those without. The spectrum of CI in HF is similar to that observed in the general population and may range from delirium to isolated memory or non-memory-related deficits to dementia.
Kannayiram, Alagiakrishnan +3 more
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Cognitive Decline Associated with Aging
2023Cognitive decline is one of the most distinct signs of aging, and age-related cognitive decline is a heterogeneous issue varying in different cognitive domains and has significant differences among older adults. Identifying characteristics of cognitive aging is the basis of cognitive disease for early-detection and healthy aging promotion.
Yiru, Yang +3 more
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Phosphodiesterase Inhibition in Cognitive Decline
Journal of Alzheimer's Disease, 2014Understanding the cellular and molecular processes involved in learning and memory will help in the development of safe and effective cognitive enhancers. The cAMP response element-binding (CREB) may be a universal modulator of processes required for memory formation, and increasing the levels of second messengers like cAMP and cGMP could ultimately ...
Carolina, García-Barroso +8 more
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Surgical menopause and cognitive decline
Climacteric, 2014Aging is the strongest risk factor for cognitive decline. The perimenopausal period puts women in a more vulnerable state in regard to certain functions such as memory. Also, the Women's Health Initiative Memory Study (WHIMS) pointed at some cognitive adverse effects of postmenopausal hormone therapy, but these results were not relevant for the peri ...
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