Correlation between ankle‐brachial index and subtle cognitive decline [PDF]
Brain and Behavior, 2023 Background Subtle cognitive decline (SCD) is considered the early stage of Alzheimer's disease (AD) and is of great clinical significance for the prevention and treatment of AD.
Hui‐Feng Guo +4 more
doaj +5 more sources
Objective subtle cognitive decline and plasma phosphorylated tau181: Early markers of Alzheimer's disease‐related declines [PDF]
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 2021 Introduction Objectively‐defined subtle cognitive decline (Obj‐SCD) and plasma phosphorylated‐tau181 (p‐tau181) are promising early Alzheimer's disease (AD) markers.
Kelsey R. Thomas +7 more
doaj +8 more sources
A comparative study on the validations of three cognitive screening tests in identifying subtle cognitive decline [PDF]
BMC Neurology, 2020 Background Subtle cognitive decline (SCD) may represent a very early stage of objective cognitive impairment before mild cognitive impairment (MCI), with less neuronal damage and more functional reservation.
Feng-Feng Pan +4 more
doaj +7 more sources
Tau levels are higher in objective subtle cognitive decline but not subjective memory complaint [PDF]
Alzheimer’s Research & Therapy, 2022 Background The 2018 NIA-AA Alzheimer’s Disease (AD) Research Framework states that subtle cognitive decline in cognitively unimpaired individuals can be measured by subjective reports or evidence of objective decline on neuropsychological measures.
Kelsey R. Thomas +8 more
doaj +6 more sources
Increased regional white matter hyperintensity volume in objectively-defined subtle cognitive decline and mild cognitive impairment [PDF]
Neurobiology of Aging, 2022 White matter hyperintensities (WMH), a marker of small vessel cerebrovascular disease, increase risk of developing mild cognitive impairment (MCI) and Alzheimer's disease (AD).
Katherine Bangen +2 more
exaly +8 more sources
Local Functional MR Change Pattern and Its Association With Cognitive Function in Objectively-Defined Subtle Cognitive Decline [PDF]
Frontiers in Aging Neuroscience, 2021 Introduction: To identify individuals with preclinical cognitive impairment, researchers proposed the concept of objectively-defined subtle cognitive decline (Obj-SCD).
Liang Cui +3 more
doaj +5 more sources
Influence of daily life and health profile in subtle cognitive decline of women residing in Spanish religious communities: DeCo religious orders study [PDF]
Frontiers in Public HealthBackgroundPrior to the onset of dementia, individuals commonly undergo a phase marked by subtle cognitive changes, known as subtle cognitive decline.
Teresa Lopez de Coca +10 more
doaj +3 more sources
Prediction of Subtle Cognitive Decline in Normal Aging: Added Value of Quantitative MRI and PET Imaging [PDF]
Frontiers in Aging Neuroscience, 2021 Quantitative imaging processing tools have been proposed to improve clinic-radiological correlations but their added value at the initial stages of cognitive decline is still a matter of debate.
Panteleimon Giannakopoulos +10 more
doaj +7 more sources
Related amyloid burden and cortical atrophy in individuals with subtle cognitive decline [PDF]
Journal of Neuroimaging, 2022 Abstract Background and Purpose Subtle cognitive decline represents a stage of cognitive deterioration in which pathological biomarkers may be present, including early cortical atrophy and amyloid deposition.
Leslie Ann D Brick +2 more
exaly +4 more sources
Multimodal biomarker characterization of amnestic objective subtle cognitive decline in aging and preclinical Alzheimer’s disease [PDF]
The Journal of Prevention of Alzheimer's DiseaseBackground: The objective of this study was to provide a multimodal biomarker characterization of amnestic objective subtle cognitive decline (obj-SCD) in aging and preclinical Alzheimer’s disease (AD). Methods: Prospective observational study; data from
David López-Martos +18 more
doaj +2 more sources