Results 131 to 140 of about 3,053,942 (361)
Cognitive computational neuroscience [PDF]
arXiv, 2018 To learn how cognition is implemented in the brain, we must build computational models that can perform cognitive tasks, and test such models with brain and behavioral experiments. Cognitive science has developed computational models of human cognition, decomposing task performance into computational components. However, its algorithms still fall short
arxiv
Histone Deacetylase 6 Brain PET in Amyotrophic Lateral Sclerosis‐Frontotemporal Spectrum Disorder
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective [18F]EKZ‐001 is a positron emission tomography (PET) tracer targeting histone deacetylase 6 (HDAC6), an enzyme responsible for intracellular transport and clearance of misfolded proteins. HDAC6 modulation is a promising treatment strategy in neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS).
Greet Vanderlinden +15 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Amygdala enlargement has been the subject of controversial studies regarding its significance in terms of pathogenicity both in epilepsy and in psychiatric comorbidities such as anxiety, depression, and post‐traumatic stress disorder.
Hélène Mourre +15 more
wiley +1 more source
A Brain-Inspired Compact Cognitive Mapping System [PDF]
arXiv, 2019 As the robot explores the environment, the map grows over time in the simultaneous localization and mapping (SLAM) system, especially for the large scale environment. The ever-growing map prevents long-term mapping. In this paper, we developed a compact cognitive mapping approach inspired by neurobiological experiments. Inspired from neighborhood cells,
arxiv
Behaviour-based Knowledge Systems: An Epigenetic Path from Behaviour to Knowledge [PDF]
, 2002 In this paper we expose the theoretical background underlying our current research. This consists in the development of behaviour-based knowledge systems, for closing the gaps between behaviour-based and knowledge-based systems, and also ...
Gershenson, Carlos
core +2 more sources
Translating Muscle RNAseq Into the Clinic for the Diagnosis of Muscle Diseases
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Approximately half of patients with hereditary myopathies remain without a definitive genetic diagnosis after DNA next‐generation sequencing (NGS). Here, we implemented transcriptome analysis of muscle biopsies as a complementary diagnostic tool for patients with muscle disease but no definitive genetic diagnosis after exome ...
Alba Segarra‐Casas +24 more
wiley +1 more source
An Exploration of the Dynamic Relationship between Health and Cognitive Development in Adolescence [PDF]
This paper is an empirical exploration of the dynamic relationship between health and cognitive development in a longitudinal data set compiled from two nationally representative cross-sections of children.
Linda N. Edwards +2 more
core
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD) can radiographically mimic multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD). The disease hallmarks cortical lesion, central vein sign (CVS) and paramagnetic rim lesions identified in MS have not yet been comprehensively investigated in ...
Lei Su +19 more
wiley +1 more source
A Spectrum-Shaping Perspective on Cognitive Radio [PDF]
arXiv, 2008 A new perspective on cognitive radio is presented, where the pre-existent legacy service is either uncoded or coded and a pair of cognitive transceivers need be appropriately deployed to coexist with the legacy service. The basic idea underlying the new perspective is to exploit the fact that, typically, the legacy channel is not fully loaded by the ...
arxiv