Results 41 to 50 of about 3,114,900 (278)

The Role of Social Support in Mediating Stress and Depression

open access: yesOnline Journal of Health & Allied Sciences, 2017
As important as it is to fully comprehend the relationship between stress and depression among university students, it is also vital to ascertain the role of perceived social support as an essential psychosocial factor for effectively delimiting the ...
Prashanth Talwar   +5 more
doaj  

Modelling the Developing Mind: From Structure to Change [PDF]

open access: yes, 1999
This paper presents a theory of cognitive change. The theory assumes that the fundamental causes of cognitive change reside in the architecture of mind. Thus, the architecture of mind as specified by the theory is described first.
Demetriou, Andreas   +1 more
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Reconnoitering the Influence of Socio-demographic Factors on Internet Addiction

open access: yesOnline Journal of Health & Allied Sciences, 2018
Internet addiction (IA) has gradually emerged as a detrimental mental health problem, especially amongst youngsters. The current study endeavored to ascertain the determinants of IA amidst this at-risk population, by conducting an exploratory cross ...
Prashanth Talwar   +5 more
doaj  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Performance-Based Pay: An Empirical Study in Malaysian Federal Government Linked Companies, Kuching, Sarawak

open access: yesMalaysian Management Journal, 2008
Compensation management literature highlights that properly administering performance-based pay may directly affect employee attitudes and behaviours (i.e. job performance and job turnover).
Azman Ismail   +4 more
doaj  

Master and disciple in Konjaku Monogatari-shū

open access: yesЯпонские исследования
The paper considers the theme of tutorship, which is one of the cross-cutting issues in Konjaku Monogatari-shū, a 12th century collection of setsuwa didactic tales.
M. V. Babkova, M. S. Kolyada
doaj   +1 more source

INTERSTAARS: Attention training for infants with elevated likelihood of developing ADHD: A proof-of-concept randomised controlled trial

open access: yesTranslational Psychiatry, 2021
Attention-deficit/hyperactivity disorder (ADHD) is first diagnosed during middle childhood, when patterns of difficulty are often established. Pre-emptive approaches that strengthen developing cognitive systems could offer an alternative to post ...
Amy Goodwin   +19 more
doaj   +1 more source

A Roadmap for Integrating Neuroscience into Addiction Treatment:A Consensus of the Neuroscience Interest Group of the International Society of Addiction Medicine [PDF]

open access: yes, 2019
Although there is general consensus that altered brain structure and function underpins addictive disorders, clinicians working in addiction treatment rarely incorporate neuroscience-informed approaches into their practice.
Arunogiri, Shalini   +25 more
core   +7 more sources

The role of lipid metabolism in neuronal senescence

open access: yesFEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari   +2 more
wiley   +1 more source

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