Results 61 to 70 of about 3,148,629 (296)

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Childhood socioeconomic status is associated with psychometric intelligence and microstructural brain development

Communications Biology, 2021
Takeuchi et al perform cross-sectional and longitudinal analyses of associations between childhood socioeconomic status and psychometric intelligence as well as microstructural brain development in Japanese children. They report that higher socioeconomic
Hikaru Takeuchi, Yasuyuki Taki, Kohei Asano, Michiko Asano, Yuko Sassa, Susumu Yokota, Yuka Kotozaki, Rui Nouchi, Ryuta Kawashima   +8 more
doaj   +1 more source

Using a cognitive architecture to examine what develops [PDF]

, 2000
Different theories of development propose alternative mechanisms by which development occurs. Cognitive architectures can be used to examine the influence of each proposed mechanism of development while keeping all other mechanisms constant.
Anderson J.R., Baxter G.D., Case R., David J. Wood, Elman J.L., Frank E. Ritter, Gary Jones, Gentner D., Halford G.S., Jones G., Jones G., Klahr D., McClelland J.L., Newell A., Piaget J., Reichgelt H., Shultz T.R., Siegler R.S., Siegler R.S., Siegler R.S., Siegler R.S., Simon T.J., Sternberg R.J.   +22 more
core   +2 more sources

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Heuristic Evaluation: Comparing Generic and Specific Usability Heuristics for Identification of Usability Problems in a Living Museum Mobile Guide App

Advances in Human-Computer Interaction, 2018
This paper reports on an empirical study that compares two sets of heuristics, Nielsen’s heuristics and the SMART heuristics in the identification of usability problems in a mobile guide smartphone app for a living museum.
Mohd Kamal Othman, Muhd Nur Shaful Sulaiman, Shaziti Aman   +2 more
doaj   +1 more source

Modulation of EEG theta by naturalistic social content is not altered in infants with family history of autism

Scientific Reports, 2022
Theta oscillations (spectral power and connectivity) are sensitive to the social content of an experience in typically developing infants, providing a possible marker of early social brain development.
Rianne Haartsen, Tony Charman, Greg Pasco, Mark H. Johnson, Emily J. H. Jones, The BASIS Team   +5 more
doaj   +1 more source

Effects of non-pharmacological or pharmacological interventions on cognition and brain plasticity of aging individuals. [PDF]

, 2014
Brain aging and aging-related neurodegenerative disorders are major health challenges faced by modern societies. Brain aging is associated with cognitive and functional decline and represents the favourable background for the onset and development of ...
Cesinaro, Stefano, Esposito, Roberto, Frazzini, Valerio, Pieramico, Valentina, Sensi, Stefano L   +4 more
core   +2 more sources

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source

The self-reference memory bias is preceded by an other-reference bias in infancy

Nature Communications
One of the most established biases in human memory is that we remember information better when it refers to ourselves. We investigated the development of this self-reference effect and its relationship with the emergence of a self-concept.
Charlotte Grosse Wiesmann, Katrin Rothmaler, Esra Hasan, Kathrine Habdank, Chen Yang, Emanuela Yeung, Victoria Southgate   +6 more
doaj   +1 more source