Results 41 to 50 of about 3,148,629 (296)

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

The Role of Social Support in Mediating Stress and Depression

Online Journal of Health & Allied Sciences, 2017
As important as it is to fully comprehend the relationship between stress and depression among university students, it is also vital to ascertain the role of perceived social support as an essential psychosocial factor for effectively delimiting the ...
Prashanth Talwar, Mohammed Kamal Othman, Kartini Abdul Ghan, Tan Kock Wah, Shaziti Aman, Nur Fatihah Mat Yusoff   +5 more
doaj  

Measuring neurodevelopment of inhibitory control in children using naturalistic virtual reality

Scientific Reports
Inhibitory control develops over time and is linked to fronto-striatal maturation. Traditional computerised assessments often lack ecological validity and are not age appropriate.
Larisa-Maria Dina, Paola Pinti, Tim J. Smith   +2 more
doaj   +1 more source

The Long Term Impact of Micronutrient Supplementation during Infancy on Cognition and Executive Function Performance in Pre-School Children [PDF]

, 2015
Brain growth and development are critically dependent on several micronutrients. During early development cellular activity may be sensitive to micronutrient deficiencies, however the evidence from human studies is equivocal.
Dillon, Stephanie, Lazarte, Fabiola, Lowe, Nicola M, Qualter, Pamela, Warthon-medina, Marisol, Zavaleta, Nelly   +5 more
core   +2 more sources

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Reconnoitering the Influence of Socio-demographic Factors on Internet Addiction

Online Journal of Health & Allied Sciences, 2018
Internet addiction (IA) has gradually emerged as a detrimental mental health problem, especially amongst youngsters. The current study endeavored to ascertain the determinants of IA amidst this at-risk population, by conducting an exploratory cross ...
Prashanth Talwar, Surena Sabil, Mohamed Sharif Mustaffa, Mohd Kamal Othman, Chai Chiun Hian, Shaziti Aman   +5 more
doaj  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Performance-Based Pay: An Empirical Study in Malaysian Federal Government Linked Companies, Kuching, Sarawak

Malaysian Management Journal, 2008
Compensation management literature highlights that properly administering performance-based pay may directly affect employee attitudes and behaviours (i.e. job performance and job turnover).
Azman Ismail, Dayang Nailul Munna Abang Abdullah, Norazila Abd. Aziz, Amat Khairulizan Amat Aswadi, Mohd Noor Mohd Shariff   +4 more
doaj  

Master and disciple in Konjaku Monogatari-shū

Японские исследования
The paper considers the theme of tutorship, which is one of the cross-cutting issues in Konjaku Monogatari-shū, a 12th century collection of setsuwa didactic tales.
M. V. Babkova, M. S. Kolyada
doaj   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source