Results 91 to 100 of about 10,543,697 (281)

Advancing Age Modulates Associations Between Cognitive Impairment and Brain Volumes in Early MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Cognitive impairment is common in multiple sclerosis (MS), but manifestations following the first demyelinating event are relatively unexplored. We investigated cross‐sectional associations between magnetic resonance imaging (MRI)–derived brain volumes and the presence of cognitive impairment outcomes five years after the first ...
Piriyankan Ananthavarathan, Marco Pitteri, Michael Foster, Sara Collorone, Sara Salama, Elisa Colato, Ferran Prados, Baris Kanber, Marios Yiannakas, Claudia A. M. Gandini Wheeler‐Kingshott, Indran Davagnanam, Frederik Barkhof, Declan Chard, Olga Ciccarelli, Ahmed Toosy   +14 more
wiley   +1 more source

Multi-cohort machine learning identifies predictors of cognitive impairment in Parkinson’s disease

npj Digital Medicine
Cognitive impairment is a frequent complication of Parkinson’s disease (PD), affecting up to half of newly diagnosed patients. To improve early detection and risk assessment, we developed machine learning models using clinical data from three independent
Rebecca Ting Jiin Loo, Lukas Pavelka, Graziella Mangone, Fouad Khoury, Marie Vidailhet, Jean-Christophe Corvol, Enrico Glaab, On behalf of the NCER-PD Consortium   +7 more
doaj   +1 more source

Subjective memory complaints at age 90 + in relation to cognition and risk of incident dementia: The 90 + Study

International Psychogeriatrics
Background and aims: Associations of Subjective Memory Complaints (SMC) with cognition and future dementia are poorly understood in the oldest old (age 90 +), who have high incidence and prevalence of cognitive impairment.
Zarui A. Melikyan, Ph.D., Colette Aguirre, MPH, Zeinah Al-darsani, MS, Katherine A. Colcord, PT, DPT, Annlia Paganini-Hill, Ph.D., Sarah E. Tomaszewski Farias, Ph.D., Luohua Jiang, M.D., Ph.D., Claudia H. Kawas, M.D., María M. Corrada, Sc.D.   +8 more
doaj   +1 more source

Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons, Nuria Guillen, Jordi Sarto, Neus Falgàs, Sergi Borrego‐Écija, Diana Esteller‐Gauxax, Magda Castellví, Adrià Tort‐Merino, Agnès Pérez‐Millan, Anna Antonell, Josep M. Augè Fradera, Gerard Piñol, Iolanda Riba, Anna Carnes‐Vendrell, Marta Cullell, Maria Teresa Osuna, Lorena Bajo, Teresa Romero, Eva Bonjoch, Joan Bello, Susana Fernández, Marta Balagué, Isabel Gómez‐Ruiz, Anuncia Boltes, Claustre Pont, Raquel Cuevas, Sara Carrillo, Laura Iglesias, Teresa Maria Casadevall Codina, Lorena Grau Guinea, Fernando Jose Espada, Raquel Sánchez‐Valle, Mircea Balasa, Albert Lladó   +33 more
wiley   +1 more source

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio, Desiree Latella, Lilla Bonanno, Paulo Cezar Rocha dos Santos, Marcos Maldonado‐Díaz, Meir Plotnik, Rosaria De Luca, Angelo Quartarone, Rocco Salvatore Calabrò   +8 more
wiley   +1 more source

Should we include dementia diagnosis or cognitive impairment to predict home care cost? An observational study using real-world data

BMC Health Services Research
Background The reintroduction of dementia diagnosis into Medicare Advantage risk-adjustment models suggests that the condition independently influences Medicare costs.
Flurina Meier-Schwarzer, Nicole Probst-Hensch, Marc Höglinger, Matthias Schwenkglenks, Simon Wieser   +4 more
doaj   +1 more source

A Sequential Generalized Nonparametric Classification Method for Small-Scale Cognitive Diagnostic Assessment

Behavioral Sciences
Small-scale (e.g., classroom) assessment represents the most common and needed scenario for cognitive diagnostic testing. In such settings, polytomously scored items (e.g., constructed-response tasks) are widely used, as they provide more fine-grained ...
Junjie Li, Huijing Zheng, Chunhua Kang, Yan Cai, Dongbo Tu   +4 more
doaj   +1 more source

Model of Care for People with Mental Disorder and Co-existing Substance Use Disorder (Dual Diagnosis)

, 2023
This Model of Care has been developed in partnership with HSE Social Inclusion, HSE Health and Wellbeing and the National Office of Suicide Prevention and in collaboration with voluntary bodies including Sec.39 agencies.
National Working Group for Dual Diagnosis
core  

Acute Kidney Injury After Mechanical Thrombectomy for Stroke in Patients With Pre‐Existing Renal Impairment

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Acute kidney injury (AKI) is a common but often underrecognized complication in ischemic stroke patients undergoing mechanical thrombectomy, particularly among those with pre‐existing renal impairment. This study evaluated the incidence, risk factors, and clinical impact of AKI in this high‐risk population.
Michał Borończyk, Marcel Pilarek, Emilia Jaworska, Natalia Kardas, Oliwia Barnaś, Julia Woźniak, Iga Machała, Julia Węgrzynek‐Gallina, Joanna Siuda, Anna Hawrot‐Kawecka, Anetta Lasek‐Bal   +10 more
wiley   +1 more source

Diagnosis of Alzheimer’s Disease and Mild Cognitive Impairment Using Convolutional Neural Networks

Journal of Alzheimer's Disease Reports
Background: Alzheimer’s disease and mild cognitive impairment are common diseases in the elderly, affecting more than 50 million people worldwide in 2020.
Sara Ghasemi Dakdareh, Karim Abbasian
doaj   +1 more source