Results 161 to 170 of about 150,614 (260)

Animal models for investigating post‐stroke cognitive impairment: A neurovascular trafficking perspective

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Animal models enable mechanistic testing of how ischemic injury disrupts neurovascular trafficking and drives cognitive vulnerability after stroke. Complementary models capture distinct vascular, cellular, white matter, and cognitive features of PSCI.
Pratchaya Kaewkaen
wiley   +1 more source

Understanding the Pattern of Cognitive Decline in GBA1‐Related Parkinson's Disease: An Exploratory Longitudinal Multi‐Cohort Study

open access: yesAnnals of Neurology, EarlyView.
Objective People with Parkinson's disease (PD) who carry a pathogenic GBA1 variant (PDGBA1) are at higher risk of cognitive impairment than those without the variant (PDGBA1_wildtype). To date, little is known about the pattern and evolution of cognitive decline in PDGBA1. This multicenter study characterized the cognitive profile of PDGBA, focusing on
Merle Bode   +345 more
wiley   +1 more source

Rate and Shape of Functional Decline in Amyotrophic Lateral Sclerosis Identify Clinically Distinct Amyotrophic Lateral Sclerosis Phenotypes

open access: yesAnnals of Neurology, EarlyView.
Objective The ALS Functional Rating Scale–Revised decline rate compresses trajectory shape into a single number, potentially missing distinct phenotypes. We tested whether shape identifies phenotypes that rate does not distinguish, and whether post‐hoc analysis recovers a hidden ultrarapid subgroup. Methods From the Piemonte and Valle d'Aosta register (
Andrea Calvo   +20 more
wiley   +1 more source

An operant-based touchscreen morph discrimination task does not detect age-related mnemonic similarity deficits in rats. [PDF]

open access: yesOxf Open Neurosci
Ross A   +9 more
europepmc   +1 more source

Prediction of First and Recurrent Falls in Parkinson's Disease

open access: yesAnnals of Neurology, EarlyView.
Objective To develop and externally validate prediction models for next‐year falls in Parkinson's disease (PD), and to evaluate the incremental value of imaging and fluid biomarkers. Methods We developed models in Parkinson's Progression Markers Initiative (PPMI) to predict next‐year falls with external validation in University of Pennsylvania (UPenn ...
Joaquin A. Vizcarra   +13 more
wiley   +1 more source

Expert‐validated criteria for evaluating 2D anatomical images: Results of a Delphi consensus study

open access: yesAnatomical Sciences Education, EarlyView.
Abstract Currently, there are no consensus standards for the selection of two‐dimensional (2D) anatomical images that form the basis of anatomy education. The absence of standardized evaluation criteria may contribute to variability in image quality and inconsistencies in the educational use of anatomical visuals, potentially affecting students ...
Ayşe Soylu   +3 more
wiley   +1 more source

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