Results 71 to 80 of about 1,501,382 (305)

Probiotics Enhance FOLFOX Efficacy Via Gut Bacterial Tryptophan Metabolism in Colorectal Cancer [PDF]

BIO Web of Conferences
FOLFOX is the recommended regimen for CRC chemotherapy, but its response rate is limited. Our previous studies confirmed that intestinal microbiota is strongly associated with FOLFOX's anti-CRC effect, but the underlying mechanism remains unclear.
Deng Yufei, Hou Xiaoying, Chen Kailing, Shao Tong, Liu Yuchen   +4 more
doaj   +1 more source

Glymphatic Dysfunction Reflects Post‐Concussion Symptoms: Changes Within 1 Month and After 3 Months

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mild traumatic brain injury (mTBI) may alter glymphatic function; however, its progression and variability remain obscure. This study examined glymphatic function following mTBI within 1 month and after 3 months post‐injury to determine whether variations in glymphatic function are associated with post‐traumatic symptom severity ...
Eunkyung Kim, Han Gil Seo, Roh‐Eul Yoo, Byung‐Mo Oh   +3 more
wiley   +1 more source

Lateral hypothalamus orexinergic projection to the medial prefrontal cortex modulates chronic stress-induced anhedonia but not anxiety and despair

Translational Psychiatry
Chronic stress-induced anxiodepression is a common health problem, however its potential neurocircuitry mechanism remains unclear. We used behavioral, patch-clamp electrophysiology, chemogenetic, and optogenetic approaches to clarify the response of the ...
Danlei Liu, Xuefeng Zheng, Yuqing Hui, Yuanyuan Xu, Jinjiang Du, Zean Du, Yichen Che, Fengming Wu, Guangyin Yu, Jifeng Zhang, Xiaobing Gong, Guoqing Guo   +11 more
doaj   +1 more source

A case report of ruptured intracranial dissecting aneurysm associated with neurosyphilis

Interdisciplinary Neurosurgery
Intracranial dissecting aneurysm secondary to neurosyphilis is rare with only sporadic literature. Due to the insidious nature of the disease, as well as the rapid and dynamic changes of the intectious intracranial aneurysm, the outcome of treatment was ...
Ziwei Xu, Jie Chang, Jun Shu, Yiping Zhou, Aijuan Yan, Chunhui Gu, Lutian Bai, Wenshi Wei   +7 more
doaj   +1 more source

The Neurobiology of Eating Disorders. [PDF]

, 2019
Eating disorders are severe psychiatric illnesses with a typical age of onset in adolescence. Brain research in youth and young adults may help us identify specific neurobiology that contributes to onset and maintenance of those disorders.
DeGuzman, Marisa C, Frank, Guido KW, Shott, Megan E   +2 more
core  

Concepts of mental disorders in the United Kingdom : Similarities and differences between the lay public and psychiatrists [PDF]

, 2019
BACKGROUND: The lay public often conceptualise mental disorders in a different way to mental health professionals, and this can negatively impact on outcomes when in treatment.
Ben Butlin, Cooper R., Dunn S., Field A., Furnham A., Jorm A. F., Keith Laws, Matthew D Broome, McCrone P., Rebecca Read, Shivani Sharma, Sullivan P. F., Tabachnick B. G., Vossler A.   +13 more
core   +2 more sources

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani, Lakshmi Pillai, Reid D. Landes, Aliyah Glover, Shannon Doerhoff, Jennifer Kleiner, Mitesh Lotia, Rohit Dhall, Edgar Garcia‐Rill   +8 more
wiley   +1 more source

Personality Disorder Cognitions in the Eating Disorders [PDF]

Journal of Nervous & Mental Disease, 2014
Patients with eating disorder have relatively high rates of comorbid personality disorder diagnoses, including both anxiety-based personality disorders (obsessive-compulsive and avoidant) and borderline personality disorder. However, there is preliminary evidence that the core cognitions underlying personality pathology in the eating disorders are ...
Gabriel, C., Waller, G.
openaire   +3 more sources

Predicting Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex Using a Fusion Model Integrating Lesion Network Mapping and Machine Learning

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu, Qi Wang, Suhui Kuang, Dezhi Cao, Ping Ding, Shaohui Zhang, Haihua Wei, Zhirong Wei, Jinshan Xu, Xinyu Huang, Bing Liu, Shuli Liang   +11 more
wiley   +1 more source

SARS-CoV-2 Nsp7 plays a role in cognitive dysfunction by impairing synaptic plasticity

Frontiers in Neuroscience
It has been reported that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can result in long-term neurological symptoms such as cognitive dysfunction, however the specific mechanisms underlying this phenomenon remain unclear ...
Jiazheng Guo, WeiLing Li, Mengbing Huang, Jialu Qiao, Pin Wan, Yulin Yao, Lirui Ye, Ye Ding, Jianing Wang, Qian Peng, Wei Liu, Yiyuan Xia, Xiji Shu, Binlian Sun, Binlian Sun   +14 more
doaj   +1 more source