Results 41 to 50 of about 556,929 (313)

There Is No Need For A Cognitive Domain

, 2023
Cognitive Warfare is gaining ground in the strategic and operational debate. Accordingly, there are various calls for the introduction of a cognitive domain. The partitioning of warfare into operational domains within the framework of Multi-Domain Operations (MDO) effectively reduces the complexity of military decision models as long as the majority of
Hofstetter, Patrick, Jossen, Flurin
openaire   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Effects of homocysteine lowering with B vitamins on cognitive aging: meta-analysis of 11 trials with cognitive data on 22,000 individuals. [PDF]

, 2014
BACKGROUND: Elevated plasma homocysteine is a risk factor for Alzheimer disease, but the relevance of homocysteine lowering to slow the rate of cognitive aging is uncertain.
Hankey, G.J., Lewerin, Catharina,, Eussen, SJ, Sarah Parish, Hankey, GJ, Eussen, Simone J. P. M., Dangour, A. D., Halsey, Jim, Bennett, Derrick, Lewington, S., B-Vitamin Treatment Trialists' Collaboration, the, David J Stott, Lewerin, C., Dangour, Alan D, Bennett, D., Galan, P, Graeme J Hankey, B-Vitamin Treatment Trialists’ Collaboration, Dangour, A.D., Bennett, D, Eussen, Simone JPM, Lonn, E., Armitage, J., Spence, J.D., Francine Grodstein, Hankey, G. J., Parish, Sarah, Galan, P., Eussen, Sjpm, Catharina Lewerin, Alan D Dangour, de Groot, L.C., Parish, S., Eva Lonn, Hankey, Graeme J., Clarke, Robert, Halsey, J., Rory Collins, Clarke, R, Derrick Bennett, Spence, J. D., Hankey, Graeme J, Simone JPM Eussen, Spence, J. David, Collins, Rory, Sarah Lewington, Stott, David J, Armitage, Jane, Stott, D. J., Lewington, Sarah, Collins, R, Eussen, S.J., Lonn, E, Murray Skeaff, Lewerin, Catharina, Clarke, R., Robert Clarke, J David Spence, de Groot, C.P.G.M., Grodstein, Francine, Spence, J David, Pilar Galan, Jim Halsey, Eussen, S.J.P.M.; id_orcid, Spence, JD, Dangour, AD, Jane Armitage, Lonn, Eva, Armitage, J, Galan, Pilar, Lewerin, C, Collins, R., Stott, David J., Groot, C.P.G.M., de, Skeaff, M, Dangour, Alan D., Grodstein, F., Halsey, J, Grodstein, F, Skeaff, M., de Groot, LC, de Groot, Lisette C, Eussen, S.J.P.M., Lisette C de Groot, de Groot, L. C., de Groot, Lisette C., Stott, D.J., Stott, DJ, Skeaff, Murray   +88 more
core   +1 more source

The Domain of Organizational Cognitive Neuroscience [PDF]

Journal of Management, 2012
In this editorial, the authors respond to the 2011 article in the Journal of Management by Becker, Cropanzano, and Sanfey, titled “Organizational Neuroscience: Taking Organizational Theory Inside the Neural Black Box.” More specifically, the authors build on the ideas of Becker et al.
Lee, Nick, Senior, Carl, Butler, Michael
openaire   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Teaching and Learning Strategies for First-year Medical Students [PDF]

Journal of Clinical and Diagnostic Research
We read with great interest the article “Graph Constructors Versus Graph Interpreters Versus Non Graphers: A Search towards Better Cognitive Performers in Biochemistry among First-Year Medical Undergraduates,” published by Gunanithi K et al., in the July
Sarita Anil Shinde, Umesh K More
doaj   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

ÇOKLU ZEKA UYGULAMALARI DOĞRULTUSUNDA İŞLENEN CİMNASTİK VE VOLEYBOL ÜNİTELERİNİN ÖĞRENCİLERİN BİLİŞSEL VE DEVİNİŞSEL YÖNDEN GELİŞİMLERİNE OLAN ETKİSİ

Spormetre Beden Eğitimi ve Spor Bilimleri Dergisi, 2005
Bolu İli Kıbrısçık İlçesinde bulunan bir İlköğretim Okulu’nun 7. sınıf öğrencileri üzerinde yürütülen ve 11 hafta süren bu çalışmanın amacı, Çoklu Zeka Uygulamaları doğrultusunda işlenen Beden Eğitimi ve Spor derslerinin (cimnastik ve voleybol üniteleri)
Dilşad E Mirzeoğlu, Aylin İlhan, İbrahim Aktaş, Veysel Demir   +3 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

A Domain-Independent Approach of Cognitive Appraisal Augmented by Higher Cognitive Layer of Ethical Reasoning [PDF]

, 2017
According to cognitive appraisal theory, emotion in an individual is the result of how a situation/event is evaluated by the individual. This evaluation has different outcomes among people and it is often suggested to be operationalised by a set of rules
Ojha, Suman, Williams, M-A, Vitale, Jonathan, Ojha, S, Vitale, J, Williams, Mary-Anne   +5 more
core