Results 131 to 140 of about 719,356 (300)

Carboranyl‐Curcuminoids for the Neutron Capture‐Based Treatment of Amyloid Aggregates in Alzheimer's Disease

Advanced Science, EarlyView.
The 10B‐enriched monocarbonyl analog of curcumin (BMAC) 10B‐9 enables site‐specific Boron Neutron Capture Therapy (BNCT) on amyloid‐β (Aβ) fibrils. Neutron irradiation induces histidine oxidation and fibril destabilization, as revealed by 1H‐NMR and FESEM analyses.
Sebastiano Micocci, Stefano Parisotto, Diego Alberti, Alberto Lanfranco, Valeria Bitonto, Polyssena Renzi, Martina Salmi, Federica Dal Bello, Katiuscia Pagano, Laura Ragona, Nicoletta Protti, Annamaria Deagostino, Simonetta Geninatti Crich   +12 more
wiley   +1 more source

Cognitive flexibility and categorization.

, 2021
L’objectif général de cette recherche est d’évaluer l’efficacité d’un dispositif d’apprentissage qui favoriserait chez des élèves de CM2 la capacité à envisager des problèmes sous différents points de vue, à les recatégoriser, en développant leur flexibilité cognitive (Clément, 2021).
Iacono, Éric, Gros, Hippolyte, Clément, Evelyne   +2 more
openaire   +1 more source

Multimodal Wearable Biosensing Meets Multidomain AI: A Pathway to Decentralized Healthcare

Advanced Science, EarlyView.
Multimodal biosensing meets multidomain AI. Wearable biosensors capture complementary biochemical and physiological signals, while cross‐device, population‐aware learning aligns noisy, heterogeneous streams. This Review distills key sensing modalities, fusion and calibration strategies, and privacy‐preserving deployment pathways that transform ...
Chenshu Liu, Haolin Fan, Minwoo Kim, Tong Zhou, Pinyi Yang, Lingdi Zhao, Yiran Wang, Ziyuan Che, Chia‐Wei Liu, Bingbing Li, Yangzhi Zhu   +10 more
wiley   +1 more source

Exploring the interplay of stress, fatigue, and empathy: The mediating role of cognitive flexibility in enhancing the well-being of university students in medical and social disciplines.

PLoS ONE
This study investigates the interplay between stress, fatigue, and empathy among university students in medical and social disciplines, focusing on the mediating role of cognitive flexibility.
Agata Rudnik, Krzysztof Sobczak, Artur Sawicki, Agata Zdun-Ryżewska   +3 more
doaj   +1 more source

Creating a resilient pedagogy: Character strengths intervention for aspiring educators

Acta Psychologica
Teachers play a crucial role in guiding learners through life's challenges. They face educational and socio-economic shifts while striving to teach for a better future.
Gayathri Janapati, V. Vijayalakshmi
doaj   +1 more source

Leveraging cognitive flexibility through flexible categorization training

Being cognitively flexible is crucial for academic success, especially in disciplines requiringproblem-solving and abstract reasoning, such as mathematics. Therefore, investigating whetherthe expression of cognitive flexibility can be trained in specific areas of knowledge is a majorchallenge for mathematics education.
Eric IACONO, Evelyne Clément, Alain Guerrien, Hippolyte Gros   +3 more
openaire   +1 more source

Brain and Liver Dual‐Targeting Oridonin Nanoparticles to Enhance Aβ Clearance for Alzheimer's Disease Therapy

Advanced Science, EarlyView.
We developed a nanoparticle named OAF, which simultaneously targeted to both the brain and liver via the transferrin receptor 1 (TfR1) receptor, promoting lipoprotein receptor‐related protein 1 (LRP1) expression to enhance amyloid‐beta (Aβ) clearance. In AD mice model, OAF significantly reduced Aβ deposition and cognitive impairment, while a mitigating
Wenshuai Gong, Wenting Hui, Sai Qiao, Qifeng Ji, Miao Liu, Bangle Zhang, Daozhou Liu, Yumei Wu, Siyuan Zhou   +8 more
wiley   +1 more source

Stable Diffusion Models Reveal a Persisting Human–AI Gap in Visual Creativity

Advanced Science, EarlyView.
This study examines visual creativity in humans and generative AI using the TCIA framework. Human artists outperform AI overall, yet structured human guidance substantially improves AI outputs and evaluations. Findings reveal that alignment with human creativity depends critically on contextual framing, highlighting both the promise and current ...
Silvia Rondini, Claudia Alvarez‐Martin, Paula Angermair‐Barkai, Olivier Penacchio, Marc Paz, Matthew Pelowski, Dan Dediu, Antoni Rodriguez‐Fornells, Xim Cerda‐Company   +8 more
wiley   +1 more source

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

Advanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale, Marie Celine Lefevre, Alessio Carmignani, Maria Cristina Ceccarelli, Matteo Battaglini, Attilio Marino, Gianni Ciofani   +6 more
wiley   +1 more source

Relationship of perceived stress with cognitive flexibility and life satisfaction and mindfulness-based cognitive intervention in new recruits

陆军军医大学学报
Objective To explore the relationship of cognitive flexibility with perceived stress and life satisfaction in new recruits, construct a mindfulness-based cognitive intervention program, and investigate the impact of this program on cognitive flexibility ...
ZHANG Yiwei*, PENG Li, XU Chen, LI Min
doaj   +1 more source