Results 141 to 150 of about 711,556 (344)

Targeting Microglial CD49a Inhibits Neuroinflammation and Demonstrates Therapeutic Potential for Parkinson's Disease

Advanced Science, EarlyView.
This study shows that integrin receptor CD49a (Itga1 gene) is significantly upregulated in hyperactivated microglia and microglia‐specific knockdown of Itga1 rescues neuroinflammation and neurodegeneration in a chronic Parkinson's disease (PD) model by targeting PGAM5‐mediated mitochondrial dysfunction and NLRP3 activation. Targeted inhibition of CD49a
Huanpeng Lu, Yunmin Zhu, Xi Wang, Zelin Wu, Zijian Xu, Rongqing Chen, Yanwu Guo   +6 more
wiley   +1 more source

Creating a resilient pedagogy: Character strengths intervention for aspiring educators

Acta Psychologica
Teachers play a crucial role in guiding learners through life's challenges. They face educational and socio-economic shifts while striving to teach for a better future.
Gayathri Janapati, V. Vijayalakshmi
doaj   +1 more source

Cognitive flexibility and categorization.

, 2021
L’objectif général de cette recherche est d’évaluer l’efficacité d’un dispositif d’apprentissage qui favoriserait chez des élèves de CM2 la capacité à envisager des problèmes sous différents points de vue, à les recatégoriser, en développant leur flexibilité cognitive (Clément, 2021).
Iacono, Éric, Gros, Hippolyte, Clément, Evelyne   +2 more
openaire   +1 more source

Mendelian Randomization and Double Machine Learning Modeling Reveal Brain Imaging‐Derived Phenotypes as Functional Contributors to 18 Autoimmune Inflammatory Diseases

Advanced Science, EarlyView.
This schematic integrates the eight statistically significant causal relationships identified between 1,366 brain imaging‐derived phenotypes (IDPs) and 18 autoimmune inflammatory diseases (AIDs). Arrows indicate the direction of causality inferred from bidirectional two‐sample MR analyses.
Jinbin Chen, Xin Wang, Haifeng Ding, Bosheng Zheng, Keni Zeng, Chuying Hu, Jiayi Liu, Xiao Zhu, Haibing Yu   +8 more
wiley   +1 more source

Leveraging cognitive flexibility through flexible categorization training

Being cognitively flexible is crucial for academic success, especially in disciplines requiringproblem-solving and abstract reasoning, such as mathematics. Therefore, investigating whetherthe expression of cognitive flexibility can be trained in specific areas of knowledge is a majorchallenge for mathematics education.
Eric IACONO, Evelyne Clément, Alain Guerrien, Hippolyte Gros   +3 more
openaire   +1 more source

Artificial Neuron Based on Electrical Anisotropy from WSe2 Field Effect Transistors

Advanced Science, EarlyView.
An artificial neuron was realized based on the anisotropic mobility of WSe2. Dendritic and axon‐multisynaptic performance of a neuron was achieved with optical and voltage pulses. Recognition accuracy of handwritten digits was obtained to 97% based on the synaptic weight of an artificial neuron.
Qi Sun, Ping Chen, Kun Lv, Chuanwen Chen, Jinsheng Zhu, Zhiling Chen, Yaxian Lu, Ni Zhang, Zongqian Tan, Tao Lin, Caofeng Pan   +10 more
wiley   +1 more source

Correction: Open for business: how leader ambivalence facilitates upward follower communication via perceptions of increased cognitive flexibility and responsiveness [PDF]

Jana-Maria Hohnsbehn, Eileen Pauels, Iris K. Schneider   +2 more
openalex   +1 more source

Esketamine/Ketamine: Dual‐Action Mechanisms and Clinical Prospects beyond Anesthesia in Psychiatry, Immunology, and Oncology

Advanced Science, EarlyView.
Esketamine and ketamine are widely used for perioperative analgesia and anesthesia. Despite their established roles in analgesia, sedation, and anesthesia, as well as emerging antidepressant, anti‐tumor, and anti‐inflammatory effects, their clinical use is limited due to side effects and addiction potential.
Yinxin Wang, Jiangang Xu, Xinyu Zhou, Lu Che, Minghan Qiu, Yang Liu, Ming Gao, Zhen Yang   +7 more
wiley   +1 more source

Relationship of perceived stress with cognitive flexibility and life satisfaction and mindfulness-based cognitive intervention in new recruits

陆军军医大学学报
Objective To explore the relationship of cognitive flexibility with perceived stress and life satisfaction in new recruits, construct a mindfulness-based cognitive intervention program, and investigate the impact of this program on cognitive flexibility ...
ZHANG Yiwei*, PENG Li, XU Chen, LI Min
doaj   +1 more source

Cognitive flexibility in children with mild intellectual disability [PDF]

, 2012
Milica Gligorović, Nataša Buha
openalex   +1 more source