Results 21 to 30 of about 1,931,867 (302)

Cognitive frailty: Frontiers and challenges [PDF]

The Journal of nutrition, health and aging, 2013
An international consensus group comprised of investigators from the International Academy of Nutrition and Aging (IANA) and the International Association of Gerontology and Geriatrics (IAGG) recently convened in Toulouse, France to establish a definition for cognitive frailty in older adults.
A J, Woods, R A, Cohen, M, Pahor
openaire   +2 more sources

Cognitive frailty is a robust predictor of falls, injuries, and disability among community-dwelling older adults

BMC Geriatrics, 2021
Background Cognitive frailty, a combination of physical frailty and cognitive impairment, is associated with functional decline in older adults. However, there is limited information if cognitive frailty predicts the incidence of falls, injuries, and ...
Nurul Fatin Malek Rivan, Devinder Kaur Ajit Singh, Suzana Shahar, Goh Jing Wen, Nor Fadilah Rajab, Normah Che Din, Hazlina Mahadzir, Mohd Zul Amin Kamaruddin   +7 more
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Frailty and the risk of cognitive impairment [PDF]

Alzheimer's Research & Therapy, 2015
AbstractAging occurs as a series of small steps, first causing cellular damage and then affecting tissues and organs. This is also true in the brain. Frailty, a state of increased risk due to accelerated deficit accumulation, is robustly a risk factor for cognitive impairment. Community-based autopsy studies show that frail individuals have brains that
Searle, Samuel D, Rockwood, Kenneth
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Effect of various exercises on frailty among older adults with subjective cognitive concerns: a randomised controlled trial [PDF]

, 2020
Background: Physical exercise has been linked to reduced frailty, but there is insufficient evidence of beneficial effects in community-dwelling older adults with subjective cognitive concerns.
Huang Chi Hsien, Hayashi, Takahiro, Kuzuya, Masafumi, Shimada, Hiroyuki, Makino, Taeko, Kitada, Tomoharu, Uemura, Kazuki, Inoue, Aiko, Umegaki, Hiroyuki   +8 more
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Decline of ergothioneine in frailty and cognition impairment [PDF]

FEBS Letters, 2022
Ergothioneine is a well‐known antioxidant that is abundant in both human red blood cells and in fission yeast responding to nutritional stress. In frail elderly people, whose ageing organs undergo functional decline, there is a correlation between ergothioneine levels and cognitive, but not skeletal muscle decline.
Hiroshi Kondoh, Takayuki Teruya, Masahiro Kameda, Mitsuhiro Yanagida   +3 more
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The role of vitamin D in the link between physical frailty and cognitive function: A mediation analysis in community-dwelling Chinese older adults

Frontiers in Nutrition, 2022
BackgroundPhysical frailty and cognitive aging have important influences on poor clinical outcomes in older adults. Many studies have investigated the association between frailty and cognitive function, but whether vitamin D mediates the association ...
Jian Xiong, Wen-Xiong Xue
doaj   +1 more source

Longitudinal Analyses Of Frailty Trajectories Among European Older Adults [PDF]

, 2023
Frailty is a common geriatric syndrome characterized by decreased adaptability to stressors and increased vulnerability to adverse health outcomes. Frailty is not simply about ageing, but is where ageing has taken its toll.
Dinh, Linh
core   +1 more source

Cognitive Function in the Prefrailty and Frailty Syndrome [PDF]

Journal of the American Geriatrics Society, 2014
Objectives To explore the relationship between cognitive function and frailty. Design A cross‐sectional study using data from W ave 1 of The I
Robertson, Deirdre A, Savva, George M, Coen, Robert F, Kenny, Rose-Anne   +3 more
openaire   +4 more sources

Cognitive function in Prefrail and frail community-dwelling older adults in China

BMC Geriatrics, 2019
Background Physical frailty, characterized by reduced physiologic complexity and ability to cope with stressors, is closely associated with cognitive impairment, which increases the risk of poor clinical outcomes.
Lina Ma, Li Zhang, Fei Sun, Yun Li, Zhe Tang   +4 more
doaj   +1 more source

A robust machine learning framework to identify signatures for frailty: a nested case-control study in four aging European cohorts [PDF]

, 2020
Phenotype-specific omic expression patterns in people with frailty could provide invaluable insight into the underlying multi-systemic pathological processes and targets for intervention.
Zürbig, Petra, Viña, J., Zürbig, P., Lippi, G., García-Palmero, Irene, Lippi, Giuseppe, Martínez, J. G., Erusalimsky, Jorge D., Carrie, I., Carnicero, José, Sinclair, Alan J., Carnicero, J., Hardman, Timothy C., García-Palmero, I., Walter, Stefan, Abugessaisa, Imad, FEART-COURET, Catherine, Peres, Karine, Weber, Daniela, Grune, T., Peres, K., Mischak, H., Jansen-Dürr, P., Sinclair, Alan J, Walter, S., Helmer, C., Rodriguez-Mañas, L., Feart, C., Grune, Tilman, Tegner, J., Colpo, M., Miñambres-Herraiz, R., Viña, José, Fiorillo, Edoardo, Colpo, Marco, Mischak, Harald, Cesari, Matteo, Martínez, Jorge García, Butcher, Lee, Garcia-Garcia, F.J., Fiorillo, E., Cucca, Francesco, Garcia-Garcia, Francisco Jose, Hardman, Timothy C, Grillari, J., Tegner, Jesper, Weber, D., Feart, Catherine, Abugessaisa, I., Hardman, T.C., Olaso, G., on behalf of the FRAILOMIC initiative, Dartigues, J-F, Sinclair, A. J., Grillari, Johannes, Bandinelli, Stefania, Miñambres-Herraiz, Rebeca, Helmer, Catherine, Rodriguez-Mañas, Leocadio, Erusalimsky, Jorge, Bandinelli, S., Gomez-Cabrero, David, Bonaguri, C., Jansen-Dürr, Pidder, Palomares, L.B., Olaso, Gloria, Palomares, Lucia Bernad, Erusalimsky, Jorge D, Bonaguri, Chiara, Hackl, Matthias, Hackl, M., Carrie, Isabelle, Cesari, M., Cucca, F., Dartigues, Jean-François   +74 more
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