Results 81 to 90 of about 14,823,996 (352)

Cognitive Functioning in Vorinostat‐Treated Pediatric and Young Adult Patients Over the First 180 Days After Hematopoietic Stem Cell Transplant

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Cognitive and psychological difficulties could negatively interfere with treatment adherence and quality of life before and after hematopoietic stem cell transplant (HSCT). Methods to mitigate these changes may have positive effects on treatment success.
Kristen L. Votruba   +11 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Effect of nutrition on cognitive functions

open access: yesMedycyna Ogólna i Nauki o Zdrowiu, 2021
Introduction and objective Cognitive functions are the precondition of proper functioning of an organism in terms of reception and processing of stimuli coming from the environment.
Magdalena Maria Lis
doaj   +1 more source

The Recommendation Architecture: Lessons from Large-Scale Electronic Systems Applied to Cognition [PDF]

open access: yes, 2001
A fundamental approach of cognitive science is to understand cognitive systems by separating them into modules. Theoretical reasons are described which force any system which learns to perform a complex combination of real time functions into a modular ...
coward, l andrew
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Lycopene and cognitive function [PDF]

open access: yesJournal of Nutritional Science, 2019
AbstractDecreases in cognitive function related to increases in oxidative stress and inflammation occur with ageing. Acknowledging the free radical-quenching activity and anti-inflammatory action of the carotenoid lycopene, the aim of the present review was to assess if there is evidence for a protective relationship between lycopene and maintained ...
Kristi M. Crowe-White   +2 more
openaire   +3 more sources

Genome-wide association study of cognitive functions and educational attainment in UK Biobank (N=112 151)

open access: yesMolecular Psychiatry, 2016
People’s differences in cognitive functions are partly heritable and are associated with important life outcomes. Previous genome-wide association (GWA) studies of cognitive functions have found evidence for polygenic effects yet, to date, there are few ...
G. Davies   +23 more
semanticscholar   +1 more source

The Volitive and the Executive Function of Intentions [PDF]

open access: yes, 2011
Many philosophers of action conceive intentions functionally, as executive states: intentions are mental states that represent an action and tend to cause this action.
Lumer, Christoph
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

The effects of topiramate on cognitive functions of patients with focal epilepsy - a follow-up study in a Serbian sample [PDF]

open access: yesSrpski Arhiv za Celokupno Lekarstvo, 2019
Introduction/Objective. The aim of this follow-up study was to determine the effects of topiramate therapy on cognitive functions in patients with pharmacoresistant focal epilepsy. Methods. The study sample comprised of 40 topiramate naive patients.
Milošević Nenad   +7 more
doaj   +1 more source

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