Results 81 to 90 of about 580,079 (317)

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

Evolving structure-function mappings in cognitive neuroscience using genetic programming

open access: yes, 2005
A challenging goal of psychology and neuroscience is to map cognitive functions onto neuroanatomical structures. This paper shows how computational methods based upon evolutionary algorithms can facilitate the search for satisfactory mappings by ...
Parker, A, Gobet, F
core   +1 more source

Acute hypoglycemia impairs executive cognitive function in adults with and without type 1 diabetes [PDF]

open access: yes, 2013
OBJECTIVE Acute hypoglycemia impairs cognitive function in several domains. Executive cognitive function governs organization of thoughts, prioritization of tasks, and time management.
Graveling, Alex J.   +2 more
core   +1 more source

LANGUAGE FUNCTIONS IN SCHIZOPHRENIA AND N400

open access: yesPsychiatry and Clinical Psychopharmacology, 2021
One of the most prominent clinical features of schizophrenia is impaired language funct›on. Clinical studies of schizophrenia have identified poverty of content, tangentiality, distractable speech, derailment, and incoherence as features of ...
Nesim Kuğu   +2 more
doaj  

Clinical Spectrum and Outcomes of SOX1 Antibody‐Associated Paraneoplastic Neurological Syndromes: A Chinese Cohort Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background SOX1 antibody‐positive paraneoplastic neurological syndromes (PNS) exhibit significant population‐specific clinical heterogeneity. While Western cohorts predominantly manifest Lambert‐Eaton myasthenic syndrome (65%–80%), comprehensive clinical characterization and treatment response data in Asian populations remain critically ...
Jin‐Long Ye   +11 more
wiley   +1 more source

Proposing a new focus for the study of natural and artificial cognitive systems

open access: yes, 2002
In the study of systems the function of the system is often a good hint to how it works. In the following paper I would like to suggest that in studying or modeling a cognitive system our pre-knowledge of their functions should be treated carefully.
Hershberg, Uri
core  

The influence of CHRNA5 and D398N missense variation on social and emotional behaviors in rodents and humans

open access: yesTranslational Psychiatry
Social behavior alterations, notably aggressivity-related behavioral states (ARBS), and substance use disorders (SUDs) show consistent associations. In psychopathology, ARBS and SUDs cluster together as externalizing disorders, which show evidence for ...
F. de Chaumont   +10 more
doaj   +1 more source

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler   +20 more
wiley   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito   +14 more
wiley   +1 more source

Cognitive Functions Influence Lightness Perception

open access: yesi-Perception, 2012
Lightness research offers ample evidence that visual scene contains all the cues necessary to perform lightness calculations. In real life, contrary to laboratory findings, familiarity of the objects seems to be more important than the temporarily ...
Suncica Zdravkovic
doaj   +1 more source

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