Results 101 to 110 of about 4,454,503 (388)

Mild Cognitive Impairment: the Manchester consensus

Age and Ageing, 2020
Given considerable variation in diagnostic and therapeutic practice, there is a need for national guidance on the use of neuroimaging, fluid biomarkers, cognitive testing, follow-up and diagnostic terminology in mild cognitive impairment (MCI).
Ross A. Dunne, D. Aarsland, J. O'Brien, C. Ballard, Sube Banerjee, Nick C Fox, J. Isaacs, B. Underwood, R. Perry, D. Chan, T. Dening, Alan J. Thomas, Jeffrey Schryer, Anne M. Jones, A. Evans, C. Alessi, Elizabeth J Coulthard, J. Pickett, P. Elton, Roy W Jones, S. Mitchell, Nigel M. Hooper, C. Kalafatis, J. Rasmussen, Helen Martin, J. Schott, A. Burns   +26 more
semanticscholar   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Bridging the Gap: Virtual Reality as a Tool for De-Escalation Training in Disability Support Settings

Multimodal Technologies and Interaction
Managing complex behaviors in disability support settings requires competent de-escalation skills. However, the current training methods often lack sufficient opportunities for realistic practice.
Ryan Hsu, Connor McCabe, Caroline Ellison, Mark Howells, Tobias Loetscher   +4 more
doaj   +1 more source

Tau and atrophy: domain-specific relationships with cognition. [PDF]

, 2019
BackgroundLate-onset Alzheimer's disease (AD) is characterized by primary memory impairment, which then progresses towards severe deficits across cognitive domains.
Alzheimer’s Disease Neuroimaging Initiative, Banks, Sarah J, Brewer, James B, Dale, Anders M, Digma, Leonardino A, Madsen, John R, Reas, Emilie T   +6 more
core  

Semantic Memory Functional MRI and Cognitive Function After Exercise Intervention in Mild Cognitive Impairment [PDF]

, 2013
Mild cognitive impairment (MCI) is associated with early memory loss, Alzheimer\u27s disease (AD) neuropathology, inefficient or ineffective neural processing, and increased risk for AD.
Antuono, Piero, Butts, Alissa, Hanson, Ryan J., Hantke, Nathan, Lyons, Jeri-Annette, Nielson, Kristy A., Smith, J Carson, Verber, Matthew D.   +7 more
core   +2 more sources

Vascular Cognitive Impairment and Dementia: JACC Scientific Expert Panel.

Journal of the American College of Cardiology, 2019
Cognitive impairment associated with aging has emerged as one of the major public health challenges of our time. Although Alzheimer's disease is the leading cause of clinically diagnosed dementia in Western countries, cognitive impairment of vascular ...
C. Iadecola, Marco Duering, V. Hachinski, A. Joutel, S. Pendlebury, J. Schneider, M. Dichgans   +6 more
semanticscholar   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source

Spoken Language Biomarkers for Detecting Cognitive Impairment

, 2017
In this study we developed an automated system that evaluates speech and language features from audio recordings of neuropsychological examinations of 92 subjects in the Framingham Heart Study.
Alhanai, Tuka, Au, Rhoda, Glass, James
core   +1 more source

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela, Madison Reeves, Karen Jansen‐West, Judith Dunmore, Yuping Song, Audrey Strongosky, Sunil Gandhi, Gilana Pikover, Matt Blurton‐Jones, Robert C. Spitale, Erik H. Middlebrooks, Leonard Petrucelli, Mercedes Prudencio, Zbigniew K. Wszolek   +13 more
wiley   +1 more source

The importance of early immunotherapy in patients with faciobrachial dystonic seizures. [PDF]

, 2018
Faciobrachial dystonic seizures and limbic encephalitis closely associate with antibodies to leucine-rich glioma-inactivated 1 (LGI1). Here, we describe 103 consecutive patients with faciobrachial dystonic seizures and LGI1 antibodies to understand ...
Bi, Mian, Bien, Christian, Chu, Kon, Farooque, Pue, Gelfand, Jeffrey, Geschwind, Michael, Hirsch, Lawrence, Irani, Sarosh, Lang, Bethan, Leite, Maria, Makuch, Mateusz, Murchison, Andrew, Somerville, Ernest, Thompson, Julia, Vincent, Angela, Waters, Patrick   +15 more
core