Post‐Translational Modifications in Cilia and Ciliopathies
This review synthesizes current understanding of post‐translational modifications (PTMs) in ciliary proteins and emphasizes their roles in ciliary formation, homeostasis, and signaling. This review also discusses the implication of PTM dysregulation in ciliopathies and explores therapeutic strategies targeting PTM‐modifying enzymes.
Jie Ran, Jun Zhou
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Predictors of Institutionalization of Cognitively Impaired Elders: Family Help and the Timing of Placement [PDF]
Joseph E. Gaugler+6 more
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Engineered Tissue Models to Decode Host–Microbiota Interactions
Host–Microbiota interactions in the human body. Created in BioRender. Ghezzi, C. (2025) https://BioRender.com/ihivskg. Abstract A mutualistic co‐evolution exists between the host and its associated microbiota in the human body. Bacteria establish ecological niches in various tissues of the body, locally influencing their physiology and functions, but ...
Miryam Adelfio+5 more
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Mnemonics Usage and Cognitive Decline in Age-Associated Memory Impairment
Gary W. Small+3 more
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Impaired cognitive performance in drug free users of recreational ecstasy (MDMA) [PDF]
Euphrosyne Gouzoulis‐Mayfrank
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The TALENTs randomized controlled trial evaluates the potential of nucleotides supplementation as an anti‐aging intervention in older adults. After 19 weeks, nucleotides supplementation significantly reduces DNA methylation age, suggesting a delay in epigenetic aging, and improves insulin sensitivity without severe adverse events.
Shuyue Wang+9 more
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Cognitive impairment in schizophrenia:its impact on social functioning [PDF]
Peter F. Liddle
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The State of High‐Resolution Imaging of the Human Inner Ear: A Look Into the Black Box
High‐resolution imaging of the cochlea is challenged by numerous unique aspects of this organ, where sensorineural cells, crucial for hearing, are too small for conventional modalities like magnetic resonance imaging and computed tomography. This article reviews current imaging techniques, emerging technologies, and innovations aimed at improving ...
Shelley Batts+3 more
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Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine
Neural organoids provide a versatile platform for neurological research. Advances in organoid technology have partially achieved human neural tissue complexity in terms of tissue structure, cell diversity, and neural signaling, offering insights into neural disorders and regenerative strategies. Technology advances from biomaterials, bio‐manufacturing,
Ruiqi Huang+4 more
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Mild Cognitive Impairment in the Population and Physical Health: Data on 1,435 Individuals Aged 75 to 95 [PDF]
Giovanni B. Frisoni+5 more
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