Results 51 to 60 of about 3,244,747 (295)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Cognitive and Reading Profiles of Gifted Students with Learning Disabilities: Implications for Assessment and Identification

Behavioral Sciences
The identification of gifted students with learning disabilities (GLD) remains theoretically and methodologically contested. The present study examined cognitive and reading profiles of 150 Greek students in Grades 4–6, classified as gifted with learning
Susana Padeliadu, Athina Voulgari
doaj   +1 more source

The interplay between cognition, depression, anxiety, and sleep in primary Sjogren’s syndrome patients

Scientific Reports, 2022
Primary Sjögren’s syndrome (pSS) is an autoimmune disease with frequent neurological involvement. Memory complaints are common, but their precise patterns remain unclear.
Radjiv Goulabchand, Elodie Castille, Sophie Navucet, Damien Etchecopar-Etchart, Aurélie Matos, Alexandre Maria, Laure Anne Gutierrez, Alain Le Quellec, Nicolas Menjot de Champfleur, Audrey Gabelle, Philippe Guilpain   +10 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Application of the RDoC Framework to Predict Alcohol Use and Suicidal Thoughts and Behaviors among Early Adolescents in the Adolescent Brain and Cognitive Development (ABCD) Study

Brain Sciences, 2022
Alcohol use confers risk for suicidal thoughts and behaviors (ideation, attempt) in early adolescents. The Research Domain Criteria provides a framework for examination of multidimensional and modifiable risk factors. We examined distinct latent profiles
Laika D. Aguinaldo, Clarisa Coronado, Diego A. Gomes, Kelly E. Courtney, Joanna Jacobus   +4 more
doaj   +1 more source

Transitions between socio-emotional and cognitive vulnerability profiles from early to middle childhood: a population study using multi-agency administrative records [PDF]

, 2020
Adult psychosocial difficulties, including psychiatric disorders, are often preceded by childhood psychosocial vulnerabilities, presenting critical windows of opportunity for preventative intervention.
Tzoumakis, S., Laurens, KR ; https://orcid.org/, Tzoumakis, S ; https://orcid.org/, Katz, I., Harris, F., Tzoumakis, Stacy, Harris, Felicity, Carr, Vaughan J, Harris, F ; https://orcid.org/, Katz, Ilan, Green, Melissa J, Katz, I ; https://orcid.org/, Whitten, T ; https://orcid.org/, Piotrowska, Patrycja J, Laurens, K.R., Piotrowska, PJ, Carr, VJ ; https://orcid.org/, Green, MJ ; https://orcid.org/, Piotrowska, P.J., Whitten, T., Laurens, Kristin R, Carr, V.J., Green, M.J., Whitten, Tyson   +23 more
core   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

The Effects of Language Background and Parental Education on Measures of Cognitive Ability: An Analysis of the WPPSI-IV Cognitive Profiles of Monolingual, Simultaneous Bilingual, and Sequential Bilingual German Children Aged 4 to 7 Years

Children
Background: The present study investigated the possible effects of language background (monolinguals, simultaneous bilinguals, and sequential bilinguals) and parental education (no/low, medium, high, and highest parental education) on measures of ...
Franziska Walter, Monika Daseking, Franz Pauls   +2 more
doaj   +1 more source

Psychometric Characteristics of the Pictorial Test of Cognitive Profiles

, 2014
This study evaluated the psychometric properties of the Pictorial Test of Cognitive Profiles (TPPC) through the internal consistency and convergent validity of the TPPC with the Brazilian version of the Personality Belief Questionnaire – Short Form (PBQ ...
Renata Ferrarez Fernandes Lopes, Donizete Tadeu Leite, Ederaldo José Lopes, Lívia Melo Gonçalves   +3 more
core   +1 more source