Results 71 to 80 of about 628,655 (303)

Profiles of physical, emotional and psychosocial wellbeing in the Lothian birth cohort 1936 [PDF]

, 2012
Background Physical, emotional, and psychosocial wellbeing are important domains of function. The aims of this study were to explore the existence of separable groups among 70-year olds with scores representing physical function, perceived quality of ...
AE Raftery, AJ Garfein, AJ Gow, AJ Gow, AJ Lamond, AL McCuthcheon, AM Freund, Andrea R Zammit, AS Zigmond, BD Cox, C Depp, C Hertzog, CM Callahan, CR Gale, D Gerstorf, D Nagin, D Wechsler, D Wechsler, DE Schoenfeld, DJ Bauer, DK Mroczek, G Andrews, G Celeux, GJ McLachlan, H Okabayashi, HE Nelson, HS Friedman, Ian J Deary, IJ Deary, IJ Deary, IJ Deary, J Smith, J Smith, John M Starr, JW Rowe, KB DeSalvo, KE Markon, KJ Ko, KR Kruger, L Fratiglioni, L Fratiglioni, L Muthén, LF Berkman, M Lövdén, M Rennemark, MM Baltes, P Townsend, PB Baltes, PB Baltes, PT Costa, S Shiovitz-Ezra, Scottish Council for Research in Education, Scottish Council for Research in Education, ST Charles, V Menec, W Johnson, W Johnson, Wendy Johnson, WHOQOL Group, WJ Strawbridge   +59 more
core   +2 more sources

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Rethinking cognitive assessment in mild intellectual disability: evidence-based recommendations for a person-centered diagnostic framework

Health Psychology Report
This article proposes a multidimensional, person-centered framework for diagnosing mild intellectual disability (MID), chal-lenging the traditional reliance on fixed IQ thresholds as the primary diagnostic criterion. Anchored in the Cattell-Horn-Carroll (
Urszula Sajewicz-Radtke
doaj   +1 more source

Associations between lipid profiles and late‐life cognitive impairment among oldest‐old and centenarian adults

MedComm, 2023
Dyslipidemia and cognitive impairment are common among old adults and the occurrence of them rises exponentially with increasing age. Evidences of the relationships between serum lipids and cognitive impairment are inconsistent or equivocal among older ...
Yujian Chen, Kaidi Yang, Ya Huang, Xuejiao Wang, Yali Zhao, Ping Ping, Shasha Guan, Shihui Fu   +7 more
doaj   +1 more source

Fostering shared knowledge with active graphical representation in different collaboration scenarios [PDF]

, 2001
This study investigated how two types of graphical representation tools influence the way in which learners use shared and unshared knowledge resources in two different collaboration scenarios, and how learners represent and transfer shared knowledge ...
Fischer, Frank, Mandl, Heinz
core   +1 more source

Functional Connectivity Linked to Cognitive Recovery After Minor Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Patients with minor stroke exhibit slowed processing speed and generalized alterations in functional connectivity involving frontoparietal cortex (FPC). The pattern of connectivity evolves over time. In this study, we examine the relationship of functional connectivity patterns to cognitive performance, to determine ...
Vrishab Commuri, Isabella Dallasta, Ciaran Stone, Sophia Girgenti, Neda Gould, Rafael H. Llinas, Jonathan Z. Simon, Elisabeth Breese Marsh   +7 more
wiley   +1 more source

Biomedical Informatics Applications for Precision Management of Neurodegenerative Diseases [PDF]

, 2018
Modern medicine is in the midst of a revolution driven by “big data,” rapidly advancing computing power, and broader integration of technology into healthcare. Highly detailed and individualized profiles of both health and disease states are now possible,
Jimenez-Maggoria, Gustavo, Lombardo, Joseph, Miller, Justin B., Shan, Guogen   +3 more
core   +2 more sources

Profile of Cognitive Complaints in Vascular Mild Cognitive Impairment and Mild Cognitive Impairment [PDF]

ISRN Neurology, 2013
Objective. Vascular mild cognitive impairment (VaMCI) is differentiated from mild cognitive impairment (MCI) by the presence of vascular events such as stroke or small vessel disease. Typically, MCI and VaMCI patients present with subjective complaints regarding cognition; however, little is known about the specific nature of these complaints. We aimed
Jenny Gu, Corinne E. Fischer, Gustavo Saposnik, Tom A. Schweizer   +3 more
openaire   +2 more sources

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Motivation profiles in sport: A self-determination theory perspective [PDF]

, 2000
The present study examined the link between motivation profiles among adult sports participants and the outcomes of enjoyment, effort, positive and negative affect, attitude toward sport participation, intention to continue sport participation ...
Ajzen I., Aldenderfer M. S., Breckenridge J. N., Chatzisarantis N. L. D., Cohen J, Deci E. L., Deci E. L., Deci E. L., Deci E. L., Deci E. L., Deci E. L., Fortier M. S., Koestner R., Lepper M. R., McAuley E., Mummendy H. D., Norussis M. J., Pelletier L. G., Porter L. W., Ryan R. M., Ryan R. M., Ryan R. M., Ryan R. M., Ryan R. M., Schutz R. W., Tabachnick B. G., Vallerand R. J., Vallerand R. J., Vallerand R. J., Vallerand R. J., Vallerand R. J., Vallerand R. J., Vallerand R. J., Watson D.   +33 more
core   +1 more source