Results 81 to 90 of about 3,244,747 (295)

Prodromal Lewy Body Disorder Features in REM Sleep Behavior Disorder With Biomarker‐Defined Synucleinopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid eye movement sleep behavior disorder (iRBD) is a prodromal state for Lewy body disorders and exhibits biological heterogeneity that may influence clinical expression and progression. We examined clinical features in individuals with iRBD and biomarker‐defined synucleinopathy.
Daniel Weintraub, Michele K. York, Roseanne Dobkin, Anuprita R. Nair, Ryan Kurth, David‐Erick Lafontant, Chelsea Caspell‐Garcia, Roy N. Alcalay, Ethan G. Brown, Lana M. Chahine, Christopher Coffey, Tatiana Foroud, Douglas Galasko, Karl Kieburtz, Kenneth Marek, Kalpana Merchant, Brit Mollenhauer, Kathleen L. Poston, Andrew Siderowf, Cristina Simonet, Tanya Simuni, Caroline M. Tanner, Thomas F. Tropea, Aleksandar Videnovic, The Parkinson's Progression Markers Initiative   +24 more
wiley   +1 more source

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni, Cecile Pagan, Antony Citterio‐Quentin, Isabelle Rouvet, Giulia Dingeo, Cyril Hanin, Claudine Laurent‐Levinson, Samia Pichard, Bénédicte Héron, Clément Gourguechon, Daniele Mandia, Jerome Guitton, Carole Lacout, Nicolas Schleinitz, Florient Potier, Olivier Flabeau, Elsa Besse‐Pinot, Foudil Lamari, Magali Pettazzoni, Yann Nadjar   +19 more
wiley   +1 more source

From Cognitive Landscapes to Digital Hyperscapes

International Review of Research in Open and Distributed Learning, 2003
The widespread diffusion of e-Learning in organizations has encouraged the discovery of more effective ways for conveying digital information to learners, for instance, via the commonly called Learning Management Systems (LMS).
José Bidarra, Ana Dias
doaj  

Cognitive profiles in adolescents with mental retardation

, 1992
Cognitive profiles of performance were obtained from a selected group of adolescent subjects with mental retardation (MR) (n = 32; mean age: 15.4 years, S.D. = 3.7) by means of an ad hoc neuropsychological battery.
G. ALBERTINI, C. CALTAGIRONE, Caltagirone, C, Albertini, G, Vicari, S, CALTAGIRONE, CARLO, S. VICARI   +6 more
core   +1 more source

Spatial and Volumetric Characteristics of Glioblastoma: Associations With Clinical Presentation and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou, Marc Jaskir, Julian Gal, Yombe Fonkeu, Christos Davatzikos, MacLean P. Nasrallah, Jose Garcia, Rubo Xing, Stephen J. Bagley, Arati Desai, Richard E. Phillips, Steven Tobochnik, Colin A. Ellis, James J. Gugger, Nishant Sinha, Joel M. Stein, Kathryn A. Davis   +16 more
wiley   +1 more source

Comprehensive Characterization of 98 Chinese Cases of Genetic Creutzfeldt‐Jakob Disease With T188K Mutation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize the demographic, clinical, and laboratory features of the Chinese patients of genetic Creutzfeldt‐Jakob disease with T188K variant (T188K‐gCJD), the most common subtype of genetic prion diseases (gPrDs) in China. Methods In this nationwide retrospective study, data from 98 genetically confirmed T188K‐gCJD patients ...
Chun‐Jie Li, Dong‐Lin Liang, Li‐Ping Gao, Wei‐Wei Zhang, Wei Zhou, A. Ruhan, Bing Xu, Run‐Dong Cao, Kang Xiao, Cao Chen, Qi Shi, Xiao‐Ping Dong   +11 more
wiley   +1 more source

Latent profiles of childhood trauma in bipolar disorder: associations with objective and subjective cognitive functioning and quality of life

Frontiers in Psychology
IntroductionChildhood trauma is associated with a more severe clinical course in bipolar disorders; however, the latent profiles of childhood trauma and their differential impacts on cognitive functioning and quality of life remain underexplored ...
Ruoyun Ma, Ruoyun Ma, Lixia Zhong, Lixia Zhong, Duoduo Lin, Zhiyi You, Xia Luo, Xiaoling Lin   +7 more
doaj   +1 more source

Supplements for 'Unsupervised clustering reveals cognitive profiles in aphantasia'

Research materials associated with the manuscript "Unsupervised clustering reveals spatial and verbal cognitive profiles in aphantasia and typical ...
Maël Delem
core   +1 more source

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller, Vanessa Vallejo, Mónica Povedano Panadés, Orla Hardiman, Véronique Danel‐Brunaud, Senda Ajroud‐Driss, Philippe Couratier, Jeremy Shefner, Anna Gokey, Mike DiCesare, Erin Lennox, Jens Praestgaard, Lucie Brujin, Peggy Allred, Ram Miller   +14 more
wiley   +1 more source

Risk factor profiles and cognitive function in older adults: the Brain Health Support Program Study

Alzheimer’s & Dementia: Translational Research & Clinical Interventions
BACKGROUND Dementia risk factors coexist and interact in meaningful ways. Identifying risk profiles can inform prevention strategies. METHODS This study examined profiles using seven modifiable risk factors and their associations with cognition and sex ...
Caroline S. Duchaine, Manuel Montero‐Odasso, Haakon B. Nygaard, Paul W. H. Brewster, Diane M. Jacobs, Nicole D. Anderson, Penelope J. Slack, January M. Durant, Jody‐Lynn Lupo, Howard Chertkow, Howard H. Feldman, Sylvie Belleville, the Canadian Consortium on Neurodegeneration in Aging (CCNA), CAN‐THUMBS UP Study Group   +12 more
doaj   +1 more source