Results 91 to 100 of about 628,655 (303)

Characterization of Clinical Phenotype to Glial Fibrillary Acidic Protein Concentrations in Alexander Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the concentration of glial fibrillary acidic protein (GFAP) in cerebrospinal fluid (CSF) and plasma in Alexander disease (AxD) and whether GFAP levels are predictive of disease phenotypes. Methods CSF and plasma were collected (longitudinally when available) from AxD participants and non‐AxD controls.
Amy T. Waldman, Asako Takanohashi, Joshua Y. Joung, Geraldine W. Liu, Kaley Arnold, Amy Pizzino, Walter Faig, Sarah Woidill, Sona Narula, Adeline L. Vanderver   +9 more
wiley   +1 more source

Latent profiles of childhood trauma in bipolar disorder: associations with objective and subjective cognitive functioning and quality of life

Frontiers in Psychology
IntroductionChildhood trauma is associated with a more severe clinical course in bipolar disorders; however, the latent profiles of childhood trauma and their differential impacts on cognitive functioning and quality of life remain underexplored ...
Ruoyun Ma, Ruoyun Ma, Lixia Zhong, Lixia Zhong, Duoduo Lin, Zhiyi You, Xia Luo, Xiaoling Lin   +7 more
doaj   +1 more source

Clinical Spectrum and Outcomes of SOX1 Antibody‐Associated Paraneoplastic Neurological Syndromes: A Chinese Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background SOX1 antibody‐positive paraneoplastic neurological syndromes (PNS) exhibit significant population‐specific clinical heterogeneity. While Western cohorts predominantly manifest Lambert‐Eaton myasthenic syndrome (65%–80%), comprehensive clinical characterization and treatment response data in Asian populations remain critically ...
Jin‐Long Ye, Zu‐Ying Kuang, Bo Li, Meng‐Qiu Pan, Li‐Hua Zhou, Yang‐Yang Dai, Si‐Fen Xie, Xian‐Guang Lin, Ye‐Peng Hu, Li‐Hong Jiang, Zhan‐Hang Wang, Wei‐Jing Zhang   +11 more
wiley   +1 more source

From Cognitive Landscapes to Digital Hyperscapes

International Review of Research in Open and Distributed Learning, 2003
The widespread diffusion of e-Learning in organizations has encouraged the discovery of more effective ways for conveying digital information to learners, for instance, via the commonly called Learning Management Systems (LMS).
José Bidarra, Ana Dias
doaj  

Risk factor profiles and cognitive function in older adults: the Brain Health Support Program Study

Alzheimer’s & Dementia: Translational Research & Clinical Interventions
BACKGROUND Dementia risk factors coexist and interact in meaningful ways. Identifying risk profiles can inform prevention strategies. METHODS This study examined profiles using seven modifiable risk factors and their associations with cognition and sex ...
Caroline S. Duchaine, Manuel Montero‐Odasso, Haakon B. Nygaard, Paul W. H. Brewster, Diane M. Jacobs, Nicole D. Anderson, Penelope J. Slack, January M. Durant, Jody‐Lynn Lupo, Howard Chertkow, Howard H. Feldman, Sylvie Belleville, the Canadian Consortium on Neurodegeneration in Aging (CCNA), CAN‐THUMBS UP Study Group   +12 more
doaj   +1 more source

Comparing the cognitive profile of the HCI professional and the HCI educator [PDF]

, 2015
Previous research into Human-Computer Interaction (HCI) education has focussed mainly on the curriculum, pedagogy and the gap between education, and little is known about the cognitive profile of the HCI practitioner or educator, or how their individual ...
Abdelnour-Nocera, Jose, Austin, Ann
core  

Meningovascular Inflammation in Cerebral Amyloid Angiopathy‐Related Cortical Superficial Siderosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The role of inflammation in cortical superficial siderosis (cSS), a marker of cerebral amyloid angiopathy (CAA) linked to high hemorrhage risk, is unclear. We examined 15 patients with cSS using 3 T post‐contrast vessel wall MRI (VWI) and CSF analysis.
Philipp Arndt, Eya Khadhraoui, Sebastian J. Müller, Katja Neumann, Hendrik Mattern, Sven G. Meuth, Valentina Perosa, Andreas Charidimou, Stefanie Schreiber   +8 more
wiley   +1 more source

Cognitive function differs across healthy lifestyle behavior profiles: a 10-year population-based prospective cohort study

The Journal of Nutrition, Health and Aging
Background: Modifiable lifestyle behaviors significantly influence the risk of cognitive impairment. However, the cumulative effects of multidimensional lifestyle profiles on cognitive function remain poorly understood, as most studies examine individual
Huixiu Hu, Yajie Zhao, Di Guo, Ying Deng, Huanhuan Luo, Yuqing Hao, Chao Sun, Kang Yu   +7 more
doaj   +1 more source

Cognitive profile in CADASIL patients [PDF]

Journal of Neurology, Neurosurgery & Psychiatry, 2006
Age is an important predictor of clinical deterioration in CADASIL patients Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) often starts with silent lacunar infarcts or white matter changes in the third decade of life and cognitive or other neurological signs become apparent within the next 10 years.
openaire   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito, Chiara Meneghini, Alice Galli, Luca Gallo, Pierfrancesco Mitrotti, Paola Dimartino, Marianna Inglese, Cinzia Zatti, Alessandro Lupini, Andrea Pilotto, Alessandro Padovani, Micol Avenali, Enza Maria Valente, Cristina Tassorelli, Silvia P. Caminiti   +14 more
wiley   +1 more source