Results 61 to 70 of about 227,180 (304)
Journal of Family Medicine and Primary Care, 2023 Background: India will be the home of 323 million elderly persons by 2050. This means a surge in the dependent population primarily due to age-related cognitive decline.
Amandeep Kaur +3 more
doaj +1 more source
Ageing, plasticity, and cognitive reserve in connectionist networks [PDF]
, 2008 Neurocomputational modeling has suggested that a range of mechanisms can lead to reductions in functional plasticity across development (Thomas & Johnson, 2006).
Thomas, Michael S.C.
core +1 more source
Measuring cortical connectivity in Alzheimer's disease as a brain neural network pathology: Toward clinical applications [PDF]
, 2016 Objectives: The objective was to review the literature on diffusion tensor imaging as well as resting-state functional magnetic resonance imaging and electroencephalography (EEG) to unveil neuroanatomical and neurophysiological substrates of Alzheimer ...
BABILONI, CLAUDIO +6 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Does cognitive reserve shape cognitive decline? [PDF]
Annals of Neurology, 2011 AbstractObjective:Cognitive reserve is associated with a lower risk of dementia, but the extent to which it shapes cognitive aging trajectories remains unclear. Our objective is to examine the impact of 3 markers of reserve from different points in the life course on cognitive function and decline in late adulthood.Methods:Data are from 5,234 men and 2,
Archana, Singh-Manoux +5 more
openaire +4 more sources
Identifying Mechanisms of Normal Cognitive Aging Using a Novel Mouse Genetic Reference Panel
Frontiers in Cell and Developmental Biology, 2020 Developing strategies to maintain cognitive health is critical to quality of life during aging. The basis of healthy cognitive aging is poorly understood; thus, it is difficult to predict who will have normal cognition later in life. Individuals may have
Amy R. Dunn +10 more
doaj +1 more source
Cognitive reserve and emotional stimuli in older individuals: level of education moderates the age-related positivity effect. [PDF]
, 2014 UNLABELLED: BACKGROUND/STUDY CONTEXT: A frequently observed age-related effect is a preference in older individuals for positive stimuli. The cognitive control model proposes that this positivity effect may be mediated by executive functions.
Brown, AD +4 more
core +2 more sources
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Cognitive control, cognitive reserve, and memory in the aging bilingual brain
Frontiers in Psychology, 2014 In recent years bilingualism has been linked to both advantages in executive control and positive impacts on aging. Such positive cognitive effects of bilingualism have been attributed to the increased need for language control during bilingual ...
Angela eGrant, Nancy A Dennis, Ping eLi
doaj +1 more source
Effects of non-pharmacological or pharmacological interventions on cognition and brain plasticity of aging individuals. [PDF]
, 2014 Brain aging and aging-related neurodegenerative disorders are major health challenges faced by modern societies. Brain aging is associated with cognitive and functional decline and represents the favourable background for the onset and development of ...
Cesinaro, Stefano +4 more
core +2 more sources