Results 241 to 250 of about 139,057 (305)

Fine‐Tuned Regulation of mRNA Translation and Transport by STAU2 Condensate Facilitates Neuronal Development and Plasticity

Advanced Science, EarlyView.
STAU2 undergoes phase separation to form dynamic condensates that package target mRNAs and deliver them to the distal ends of growing neuronal dendrites. STAU2 condensates stabilize embedded mRNAs and repress their translation. Synaptic activity bidirectionally remodels STAU2 condensates, coordinating local translation of STAU2‐associated mRNAs ...
Shijing Huang, Yuanyuan Chu, Ruiqian Zhao, Siyu Li, Yu Feng, Hongdan Zheng, Yunli Xie, Tong Wang, Wenyu Wen   +8 more
wiley   +1 more source

Remote Magnetomechanical Neuromodulation Uncovers Therapeutic Mechanisms for Alleviating Parkinsonian Symptoms in Freely Moving Mice

Advanced Science, EarlyView.
Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters, Lorenzo Signorelli, Christian Herff, Sophia Gimple, Renzo Riemens, Gunter Kenis, Kim Rijkers, Hamed Shabani, Jyh‐Jang Sun, Yasin Temel, Hans Clusmann, Danijela Gregurec, Sarah‐Anna Hescham   +12 more
wiley   +1 more source

Cognitive Styles in Two Cognitive Sciences.

, 2012
openaire   +1 more source

Kinsenoside Targets IDH1 to Restore Microglial Immune‐Metabolic Homeostasis for Alzheimer's Disease Therapy

Advanced Science, EarlyView.
Dysregulated TCA cycle contributes to Alzheimer's disease (AD) pathogenesis. Here, we show that microglial isocitrate dehydrogenase 1 (IDH1) is a critical driver. Elevated IDH1 disrupts citrate metabolism and mitochondrial function, exacerbating AD pathology.
Qianqian Li, Yajin Liao, Yan‐bo Zhao, Hongxing Wu, Tong Jin, Shuoshuo Li, Yuhan Liu, Peng Li, Songying Ouyang, Zekai Li, YuTing Xia, Qian Hua, Rui‐Yuan Pan, Zengqiang Yuan   +13 more
wiley   +1 more source

WS2 Optoelectronic Memristive Reservoir Enabling Ultra‐Low‐Power, Multi‐Task, and Environmentally Stable Neuromorphic Computing

Advanced Science, EarlyView.
WS2‐based in‐memory sensing reservoir computing integrates sensing, memory, and computation in one compact device. It achieves ∼94% N‐MNIST, ∼93% eye motion perception, and ∼89% speech recognition with ultra‐low energy (∼25.5 fJ/spike). The system shows stability at 95% humidity, endurance over 1.5M cycles, and supports synaptic plasticity, enabling ...
Dayanand Kumar, Hanrui Li, Divyanshu Divyanshu, Dhananjay D. Kumbhar, Manoj Kumar Rajbhar, Amit Singh, Abdul Momin Syed, Selma Amara, Gianluca Setti, Nazek El‐Atab   +9 more
wiley   +1 more source

“Quick and dirty”: Intuitive cognitive style predicts trust in Didier Raoult and his hydroxychloroquine-based treatment against COVID-19

, 2020
Fuhrer J, Cova F.
europepmc   +1 more source

Relationship between Cognitive Style and Defensive Style

Perceptual and Motor Skills, 1997
This study examines psychoanalytic psychology, theories of cognitive style, and cognitive developmental psychology to examine the relationship between cognitive style and defensive style. A new set of cognitive styles of visual attention is formulated at the following developmental levels: (1) global, (2) local, (3) global-plus-local at the concrete ...
A H, Westreich, B, Ritzler, J, Duncan
openaire   +3 more sources

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Cognitive styles and religion

Current Opinion in Psychology, 2021
I discuss recent research suggesting that individual differences in cognitive style give rise to and explain religious and related supernatural and paranormal beliefs. To do so, I illustrate intuitive cognitive biases (e.g., anthropomorphism) underlying these beliefs and then review the accumulated evidence indicating that non-believers are more open ...
openaire   +2 more sources

Psychotherapy and Cognitive Style

American Journal of Psychotherapy, 1986
Patients who have a concrete cognitive style are psychotherapeutically best treated by methods that take into account their cognitive style, whether it is defensive or results from a cognitive developmental arrest. Concrete thinking, while an obstacle to insight-oriented therapy, is no obstacle to changing attitudes and behaviors by means that do not ...
M F, Weiner, J D, Crowder
openaire   +2 more sources

Cognitive style in depression

British Journal of Clinical Psychology, 1986
A revised version of the CST was validated by comparing depressed patients with anxious patients, recovered depressed and anxious patients and normal controls. Other measures included three severity of illness scales (the Beck Depression Inventory, the Hamilton Rating Scale for Depression and the state version of the State–Trait Anxiety Inventory) and ...
I M, Blackburn, S, Jones, R J, Lewin
openaire   +2 more sources