Results 41 to 50 of about 854,440 (302)

Feasibility and Safety of High‐Dose Proton Re‐Irradiation in Recurrent Pediatric Central Nervous System Tumors: A Single‐Institution Retrospective Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Pediatric central nervous system (CNS) tumors often recur despite multimodality therapy. Although re‐irradiation (re‐RT) has historically been limited by concerns for severe late toxicities, modern techniques have renewed interest in this approach. Proton therapy provides dosimetric advantages that may enable curative re‐treatment with
Jin‐Ho Song, Jonathan Baron, Carlos Chavez Perez, Sidharth Ramesh, Jane Minturn, Kavita A. Desai, Amish C. Shah, Jean M. Belasco, Kristina A. Cole, Michael J. Fisher, Phillip B. Storm, Peter M. Madsen, Goldie Kurtz, Robert A. Lustig, Christine Hill‐Kayser, Michael J. LaRiviere   +15 more
wiley   +1 more source

Emotional intelligence and optimistic cognitive style in certainty in career decision making [PDF]

, 2014
The current study tested whether Trait Emotional Intelligence variables and Optimistic Cognitive Style together predicted feelings of certainty in career decision making. Few studies have examined the effects of trait emotional intelligence or life style
Alexander, Victoria, Bartrum, Dee, Hicks, Richard E.   +2 more
core   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Cognitive Style and Self Confidence among College Students [PDF]

Journal of Studies in Social Sciences and Humanities, 2021
The cognitive process has faced deliberate changes among the common man, most notably among the college students, thereby influencing the confidence levels in their activities.
Anil Jose P S , Sijin KS
doaj  

The effects of rumination and depressive symptoms on the prediction of negative attributional style among college students [PDF]

, 2010
Research on cognitive vulnerability to depression has identified negative cognitive style and rumination as distinct risk factors for depression but how rumination would influence negative cognitive style remains unclear.
Ho, SMY, Hollon, SD, Lo, CSL
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

the Effect different type of dual task balance training on balance and cognitive function of older adults [PDF]

Journal of Kerman University of Medical Sciences
Background: The purpose of this research is to investigate the effectiveness of different training methods of dual task on balance and cognitive function in the elderly.Method: The participants in this study were 36 elderly individuals aged 65 years and ...
hesam iranmanesh, hossein shirvani, Amin Amini, Alireza Shamsoddini, vahid Sobhani   +4 more
doaj  

Relationship of Cognitive Style and Job Level: First Demonstration of Cultural Differences

Frontiers in Psychology, 2017
Higher-level managers are said to have a more intuitive cognitive style. To verify this hypothesis, we must consider three factors that have often been left out of account.
Tetsuya Kageyama, Motoaki Sugiura, Motoaki Sugiura   +2 more
doaj   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source