Results 91 to 100 of about 1,843,143 (356)

A comparison of structured and unstructured navigation through a CBT package [PDF]

open access: yes, 1990
The advent of hypertext has opened up new possibilities in computer-based training. The design of courseware without any predetermined structure could make the designer's task easier, and allow greater flexibility for the trainee to structure the ...
Ashcroft   +13 more
core   +1 more source

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler   +20 more
wiley   +1 more source

Brainstem and Cerebellar Volume Loss and Associated Clinical Features in Progressive Supranuclear Palsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel   +8 more
wiley   +1 more source

Self-Perceived Benefits of Cognitive Training in Healthy Older Adults

open access: yesFrontiers in Aging Neuroscience, 2018
The idea that individualized, computer-based cognitive training improves cognitive functioning in non-trained domains is highly contested. An understudied area is whether cognitive training improves one’s own perception of cognitive and day-to-day ...
Vina M. Goghari, Linette Lawlor-Savage
doaj   +1 more source

Training cognitive control [PDF]

open access: yes, 2018
Cognitive control over (eating) behavior is based on executive functions, an umbrella term for cognitive processes such as working memory, inhibition and cognitive flexibility. We examined whether executive functions play a role in eating behavior and weight loss, and whether these functions can be trained in order to prevent overeating.
openaire   +2 more sources

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende   +26 more
wiley   +1 more source

Efficacy of Intermittent Theta‐Burst Stimulation for Prolonged Disorders of Consciousness: A Prospective, Randomized, Controlled Trial

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Emerging evidence suggests that low‐frequency neural oscillations are dynamically regulated by consciousness levels, with the recovery of low cortical activity potentially serving as a neurophysiological substrate for conscious emergence. Targeted enhancement of these low‐frequency rhythms in patients with disorders of consciousness
Chuan Xu   +10 more
wiley   +1 more source

Educational multimedia design principles affect local and global information processing in functional brain networks

open access: yesScientific Reports
Educational multimedia has become increasingly important in modern learning environments because of its cost-effectiveness and its ability to overcome the temporal and spatial constraints of traditional methods.
Mohammadhossein Ostadi   +4 more
doaj   +1 more source

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