Results 41 to 50 of about 2,279,365 (264)

Coherent Raman scattering imaging of lipid metabolism in cancer

open access: yesJournal of Innovative Optical Health Sciences, 2023
Cancer cells dysregulate lipid metabolism to accelerate energy production and biomolecule synthesis for rapid growth. Lipid metabolism is highly dynamic and intrinsically heterogeneous at the single cell level.
Shuo Zhang, Yexuan He, Shuhua Yue
doaj   +1 more source

Waveguide-based optical parametric oscillator for coherent anti-Stokes Raman scattering [PDF]

open access: yesEPJ Web of Conferences
A Si3N4 waveguide-based optical parametric oscillator is presented that generates narrowband output pulses down to 1.44 nm and with up to 211 pJ pulse energy, allowing coherent Raman scattering spectroscopy and microscopy with sufficient spectral ...
Gao Ming   +2 more
doaj   +1 more source

Label-free evaluation of hepatic microvesicular steatosis with multimodal coherent anti-Stokes Raman scattering microscopy. [PDF]

open access: yesPLoS ONE, 2012
Hepatic microvesicular steatosis is a hallmark of drug-induced hepatotoxicity and early-stage fatty liver disease. Current histopathology techniques are inadequate for the clinical evaluation of hepatic microvesicular steatosis. In this paper, we explore
Thuc T Le   +4 more
doaj   +1 more source

Advanced Label-Free Laser Scanning Microscopy and Its Biological Imaging Application

open access: yesApplied Sciences, 2021
By eliminating the photodamage and photobleaching induced by high intensity laser and fluorescent molecular, the label-free laser scanning microscopy shows powerful capability for imaging and dynamic tracing to biological tissues and cells.
Xue Wang, Xinchao Lu, Chengjun Huang
doaj   +1 more source

Fourier-transform coherent anti-Stokes Raman scattering microscopy [PDF]

open access: yesOptics Letters, 2006
We report a novel Fourier-transform-based implementation of coherent anti-Stokes Raman scattering (CARS) microscopy. The method employs a single femtosecond laser source and a Michelson interferometer to create two pulse replicas that are fed into a scanning multiphoton microscope.
Ogilvie, Jennifer   +3 more
openaire   +3 more sources

Non-linear label-free imaging through a multimode graded index optical fibre [PDF]

open access: yesEPJ Web of Conferences, 2020
In recent years, great advances have been made in developing minimal footprint micro-endoscopes using multimode optical fibres (MMF) [1]. By employing wavefront shaping methods the seemingly random speckle pattern resulting from the guiding of coherent ...
Cifuentes Angel   +8 more
doaj   +1 more source

Advanced techniques in Raman tweezers microspectroscopy for applications in biomedicine [PDF]

open access: yes, 2008
This thesis investigates the use of Raman tweezers microspectroscopy to interrogate the biochemistry of single biological cells. Raman tweezers microspectroscopy is a powerful technique, which combines traditional Raman microspectroscopy and optical ...
Jess, Phillip R.T.
core   +2 more sources

Wide-field coherent anti-Stokes Raman scattering microscopy based on picosecond supercontinuum source

open access: yesAPL Photonics, 2018
We present a wide-field coherent anti-Stokes Raman scattering microscopy setup based on picosecond-laser-pumped supercontinuum and use it to demonstrate video-rate imaging with chemical specificity. The broadband excitation allows simultaneous imaging of
Yujie Shen   +4 more
doaj   +1 more source

Synchronized time-lens source for coherent Raman scattering microscopy

open access: yesOptics Express, 2010
We use the time-lens concept to demonstrate a new scheme for synchronization of two pulsed light sources for biological imaging. An all fiber, 1064 nm time-lens source is synchronized to a picosecond solid-state Ti: Sapphire mode-locked laser by using the mode-locked laser pulses as the clock.
Wang, Ke   +5 more
openaire   +4 more sources

Multiple surface plasmon resonances enhanced nonlinear optical microscopy

open access: yesNanophotonics, 2019
The nonlinear optical microscopies of coherent two-photon excited fluorescence and anti-Stokes Raman scattering are strongly enhanced by multiple surface plasmon resonances (MSPRs).
Mi Xiaohu   +5 more
doaj   +1 more source

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