Results 51 to 60 of about 2,279,365 (264)

Ultrasensitive Vibrational Imaging of Retinoids by Visible Preresonance Stimulated Raman Scattering Microscopy

open access: yesAdvanced Science, 2021
High‐sensitivity chemical imaging offers a window to decipher the molecular orchestra inside a living system. Based on vibrational fingerprint signatures, coherent Raman scattering microscopy provides a label‐free approach to map biomolecules and drug ...
Minghua Zhuge   +10 more
doaj   +1 more source

Visualization of Lipid Droplets in the Alveolar Macrophage Cell Line MH-S with Live-cell Imaging by 3D Holotomographic Microscopy (Nanolive)

open access: yesBio-Protocol, 2023
Lipid droplets (LD), triglycerides and sterol esters among them, are well known for their capacity as lipid storage organelles. Recently, they have emerged as critical cytoplasmic structures involved in numerous biological functions.
Andrea Pérez-Montero   +4 more
doaj   +1 more source

Coherent anti-Stokes Raman scattering microscopy of single nanodiamonds [PDF]

open access: yesNature Nanotechnology, 2014
Nanoparticles have attracted enormous attention for biomedical applications as optical labels, drug-delivery vehicles and contrast agents in vivo. In the quest for superior photostability and biocompatibility, nanodiamonds are considered one of the best choices due to their unique structural, chemical, mechanical and optical properties.
Pope, Iestyn   +7 more
openaire   +3 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Phase-sensitive detection in Raman Tweezers: biological applications [PDF]

open access: yes, 2008
In the biomedicine field, scientists act as detectives working hard to unravel the mysteries surrounding cells. To this end, Raman spectroscopy has revealed itself particularly useful, providing information concerning both the chemical composition and ...
De Luca, Anna Chiara
core   +1 more source

Thousand foci coherent anti-Stokes Raman scattering microscopy

open access: yesAPL Photonics
We demonstrate coherent anti-Stokes Raman scattering (CARS) microscopy with 1089 foci, enabled by a high repetition rate amplified oscillator and an optical parametric amplifier.
Dominykas Gudavičius   +2 more
doaj   +1 more source

Shedding new light on lipid biology with coherent anti-Stokes Raman scattering microscopy

open access: yesJournal of Lipid Research, 2010
Despite the ubiquitous roles of lipids in biology, the detection of lipids has relied on invasive techniques, population measurements, or nonspecific labeling. Such difficulties can be circumvented by a label-free imaging technique known as coherent anti-
Thuc T. Le, Shuhua Yue, Ji-Xin Cheng
doaj   +1 more source

High-contrast, fast chemical imaging by coherent Raman scattering using a self-synchronized two-colour fibre laser

open access: yesLight: Science & Applications, 2020
Raman-scattering microscopy: Fiber laser reduces the bulk An extremely stable fiber laser makes the high-resolution imaging technique of coherent Raman scattering (CRS) microscopy more practical for use in hospitals. CRS employs two pulsed laser beams to
Cihang Kong   +9 more
doaj   +1 more source

A Practical Noise2Noise Denoising Pipeline for High‐Throughput Raman Spectroscopy

open access: yesAdvanced Engineering Materials, EarlyView.
A lightweight and reproducible denoising pipeline for high‐throughput Raman spectroscopy is introduced, based on a 1D convolutional autoencoder trained with a Noise2Noise strategy. Using only repeated short‐exposure acquisitions, the method suppresses stochastic noise without reference spectra, enabling reliable spectral reconstruction while preserving
David Martin‐Calle   +5 more
wiley   +1 more source

Phase aspects of (broadband) stimulated Raman scattering

open access: yesReviews in Analytical Chemistry, 2012
The phase of the molecular response can be exploited to improve selectivity without sacrificing speed in both narrowband and broadband coherent anti-Stokes Raman scattering (CARS) microscopy, both of which will be considered in this review of the work ...
Offerhaus Herman L.   +4 more
doaj   +1 more source

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