Results 41 to 50 of about 79,703 (263)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Coherent Signal Direction Finding With Sensor Array Based on Back Propagation Neural Network
IEEE Access, 2019 An algorithm based on back propagation neural network and particle swarm optimization is proposed to solve the direction of arrival (DOA) estimation of coherent signals received by the sensor array in colored noise environment.
Baoyu Guo, Jiaqi Zhen
doaj +1 more source
An Improved Multiple-Toeplitz Matrices Reconstruction Algorithm for DOA Estimation of Coherent Signals [PDF]
Radioengineering, 2021 The Toeplitz matrix reconstruction algorithms exploit the row vector of an array output covariance matrix to reconstruct Toeplitz matrix, which provide the direction-of-arrival (DOA) estimation of coherent signals.
B. B. Qi, W. Li
doaj
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Novel Direction Of Arrival Estimation Method Based on Coherent Accumulation Matrix Reconstruction
Leida xuebao, 2015 Based on coherent accumulation matrix reconstruction, a novel Direction Of Arrival (DOA) estimation decorrelation method of coherent signals is proposed using a small sample.
Li Lei, Li Guo-lin, Liu Run-jie
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Fast TDOA and FDOA Estimation for Coherent Pulse Signals
International Journal of Antennas and Propagation, 2022 Time difference of arrival (TDOA) and frequency difference of arrival (FDOA) have been widely used for localizing temporally continuous signals passively.
Yan Liu, Fucheng Guo
doaj +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source