Results 61 to 70 of about 456,541 (295)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

A note on the use of coherent integration in periodogram analysis of MST radar signals [PDF]

open access: yes, 1983
The effect of coherent integration on the periodogram method to estimate the power spectra of MST radar signals is examined. The spectrum estimate usually is biased, even when care is taken to reduce the aliasing effects.
Rastogi, P. K.
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Novel Direction Of Arrival Estimation Method Based on Coherent Accumulation Matrix Reconstruction

open access: yesLeida xuebao, 2015
Based on coherent accumulation matrix reconstruction, a novel Direction Of Arrival (DOA) estimation decorrelation method of coherent signals is proposed using a small sample.
Li Lei, Li Guo-lin, Liu Run-jie
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Digital decorrelator saves time and expense in acoustic testing of structures [PDF]

open access: yes, 1971
Instantaneous signals from coherent random sound field are summed and time delayed to avoid introducing vectorial addition errors. Resultant statistically independent signals are applied to spectrometer.
Nakich, R. B., Woodbury, R. C.
core   +1 more source

Independent Component Analysis for Improved Defect Detection in Guided Wave Monitoring [PDF]

open access: yes, 2015
Guided wave sensors are widely used in a number of industries and have found particular application in the oil and gas industry for the inspection of pipework.
Cawley, P, Dobson
core   +1 more source

Effective beamformer for coherent signal reception [PDF]

open access: yesElectronics Letters, 2003
A new two-stage beamformer for coherent signal reception is proposed. The first stage extracts all the coherent signals from an antenna array using their direction-of-arrival information, and then the resultant signals are coherently combined in the second stage. Simulation results are included to demonstrate the effectiveness of the proposed technique.
Linrang Zhang   +3 more
openaire   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

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