Results 221 to 230 of about 31,924 (248)

Spatial constraints drive amylosome-mediated resistant starch degradation by Ruminococcus bromii in the human colon. [PDF]

Nat Commun
Wimmer BH, Moraïs S, Amit I, Tovar-Herrera O, Tatli M, Trautwein-Schult A, Pfister B, Zalk R, Tödtli P, Simoni S, Lisibach M, Levin L, Becher D, Bayer EA, Medalia O, Mizrahi I.   +15 more
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Lineage-determining transcription factors constrain cohesin to drive multi-enhancer oncogene regulation. [PDF]

Nat Cell Biol
Zhou Y, Jay A, Burget N, Friedrich T, Yoon S, Alsing J, Nir G, Grosschedl R, Vahedi G, Faryabi RB.   +9 more
europepmc   +1 more source

Protecting double Holliday junctions ensures crossing over during meiosis. [PDF]

Nature
Tang S, Hariri S, Bohn R, McCarthy JE, Koo J, Pourhosseinzadeh M, Nguyen E, Liu N, Ma C, Lu H, Lee M, Hunter N.   +11 more
europepmc   +1 more source

Correction to: RBM46 is essential for gametogenesis and functions in post-transcriptional roles affecting meiotic cohesin subunits. [PDF]

Protein Cell
europepmc   +1 more source

Loop extrusion creates rare, long-lived encounters underlying enhancer-promoter communication

Ubertini M, Louafi N, Landry K, Kos PI, Roth G, Marchi E, Cramard J, Tiana G, Giorgetti L.   +8 more
europepmc   +1 more source

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Cohesin in Gametogenesis

2013
Sister chromatid cohesion depends on cohesin, a tripartite complex that forms ring structures to hold sister chromatids together in mitosis and meiosis. Meiocytes feature a multiplicity of distinct cohesin proteins and complexes, some meiosis specific, which serve additional functions such as supporting synapsis of two pairs of sister chromatids and ...
François, McNicoll, Michelle, Stevense, Rolf, Jessberger   +2 more
openaire   +2 more sources

A cohesin–RAD21 interactome

Biochemical Journal, 2012
The cohesin complex holds the sister chromatids together from S-phase until the metaphase-to-anaphase transition, and ensures both their proper cohesion and timely separation. In addition to its canonical function in chromosomal segregation, cohesin has been suggested by several lines of investigation in recent years to play additional roles in ...
Anil K, Panigrahi, Nenggang, Zhang, Subhendu K, Otta, Debananda, Pati   +3 more
openaire   +2 more sources

Cohesin mutations in myeloid malignancies

Blood, 2021
Abstract Cohesin is a multisubunit protein complex that forms a ring-like structure around DNA. It is essential for sister chromatid cohesion, chromatin organization, transcriptional regulation, and DNA damage repair and plays a major role in dynamically shaping the genome architecture and maintaining DNA integrity.
Johann-Christoph Jann, Zuzana Tothova
openaire   +2 more sources