Results 51 to 60 of about 2,119,312 (119)
How to halve ploidy : lessons from budding yeast meiosis [PDF]
Maintenance of ploidy in sexually reproducing organisms requires a specialized form of cell division called meiosis that generates genetically diverse haploid gametes from diploid germ cells.
Kerr, Gary W. +3 more
core +1 more source
ABSTRACT Bicellular pollen often enters a desiccated state wherein development is temporarily arrested, enabling long‐term survival while maintaining the capacity for rapid activation upon hydration. Although the generative cell in mature pollen of Lilium species is known to have completed DNA replication, its precise cell‐cycle status and the ...
Mio K. Shibuta +2 more
wiley +1 more source
A microscopic study of cohesin [PDF]
Cohesin is a ring-shaped Smc (Structural Maintenance of Chromosomes) complex that mediates DNA-DNA interactions between chromosomes (sister chromatid cohesion) and within chromosomes (looping).
Rhodes, James, James Rhodes
core +1 more source
SOX30 Governs Synaptonemal Complex Assembly and Homologous Recombination in Male Meiosis
The transcription factor SOX30 directly binds promoter regions of SYCE1 and SYCE2 to mediate their transcriptional activation, thereby enabling proper assembly of central elements within the synaptonemal complex. Structural destabilisation of the synaptonemal complex in Sox30 KK spermatocytes triggers synaptic discontinuity, impairs homologous ...
Kangle Liu +16 more
wiley +1 more source
Homologous recombination, sister chromatid cohesion, and chromosome condensation in mammalian meiosis [PDF]
In the life cycle of sexually reproducing eukaryotes, haploid and diploid generations of cells alternate. Two types of cell division occur in such a life cycle: mitosis and meiosis. They are compared in chapter 1 .
Eijpe, M.
core
Mechanisms of cohesin protection and removal during meiosis in Saccharomyces cerevisiae [PDF]
Meiosis is a specialised form of cell division which results in the formation of haploid cells from a diploid progenitor, and thus meiosis halves the chromosome content of the parental cell.
Barton, Rachael Emilia
core +3 more sources
A central molecular adaptor, ZSL, is identified that links transverse filaments ZYP1 to central element SCEP1/2 to drive synaptonemal complex assembly in Brassica napus. Loss of ZSL abolishes synaptonemal complex formation, disrupts meiotic chromosome segregation, and markedly increases crossovers, providing mechanistic insight into meiotic fidelity ...
Miaowei Geng +16 more
wiley +1 more source
Cohesin ubiquitylation and mobilization facilitate stalled replication fork dynamics
129 p.-7 fig.-7 fig.supl.-1 tab.supl.Replication fork integrity is challenged in conditions of stress and protected by the Mec1/ATR checkpoint to preserve genome stability.
Grazia Pellicanò +13 more
core +1 more source
Cohesin-dependent regulation of gene expression during differentiation is lost in cohesin-mutated myeloid malignancies. [PDF]
Cohesin complex disruption alters gene expression, and cohesin mutations are common in myeloid neoplasia, suggesting a critical role in hematopoiesis.
Green, Anthony R. +15 more
core +3 more sources
Pds5 promotes cohesin acetylation and stable cohesin–chromosome interaction
International audiencePds5 and Wpl1 act as anti-establishment factors preventing sister-chromatid cohesion until counteracted in S-phase by the cohesin acetyl-transferase Eso1.
Javerzat, Jean-Paul +12 more
core +1 more source

