Results 41 to 50 of about 816,100 (301)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Entrepreneurial performance of the European Union - pivot of its economic security

open access: yesNew Medit, 2020
"The goal of the present paper is to demonstrate whether the varying performance of the European Union states in terms of business and entrepreneurial attractiveness and activity is diminishing the level of overall economic security.
Augustin Ignatov
doaj   +1 more source

Staff Engagement for Cohesion [PDF]

open access: yes, 2016
This chapter in a book on small and rural libraries looks at issues around why staff engagement is a concern. We discuss the barriers to staff engagement and the role professional development plays in lowering the barriers.
Ward, Jennifer, Wilkes, Bethany
core  

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Social Cohesion in Germany 2017. Bertelsmann Stiftung Study. English Summary [PDF]

open access: yes, 2018
Despite all the dire predictions, Germany continues to exhibit a high level of social cohesion. Even the country’s growing cultural and religious diversity is not at odds with its degree of togetherness.
Unzicker, Kai
core  

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

open access: yesMolecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor   +2 more
wiley   +1 more source

Examining the Relationship Between Social Cohesion and Health in Kensington [PDF]

open access: yes, 2018
This quantitative cross-sectional survey study was conducted in collaboration with the New Kensington Community Development Corporation (NKCDC) to improve our understanding of the role of social cohesion in the Somerset neighborhood.
Fossi, MPHc, Alexander   +1 more
core   +1 more source

Development of a Cohesion Questionnaire for Youth: The Youth Sport Environment Questionnaire [PDF]

open access: yes, 2009
The purpose of the current study was to initiate the development of a psychometrically sound measure of cohesion for youth sport groups. A series of projects were undertaken in a four-phase research program.
Albert V. Carron   +4 more
core   +4 more sources

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

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