Results 61 to 70 of about 816,100 (301)
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Aging and Cancer, EarlyView.Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
The Moral and Political Legitimations of War and the Complex Dynamics of Peace Negotiation Processes
Politics and GovernanceThis thematic issue investigates the moral and political legitimations of war and the complex dynamics of peace negotiation processes in contemporary international politics.
Alexander Yendell, Oliver Hidalgo
doaj +1 more source
兩篇七年級「能量塔」文本之比較分析 Evaluating Two 7th Grade Texts of “Pyramid of Energy Flow”
Journal of Research in Education Sciences, 2011 本文旨在分析比較2 篇能量塔文本的語言特性及其差異。選取七年級X、Y版生態系單元與能量塔概念有關的內容為標的文本，以逐步文本分析系統分析比較2 篇文本的基本語言、漢語及科學語言等特性之差異。研究發現，2 篇文本的詞彙密度及科學詞彙密度未達顯著差異，而科學詞彙內容則有不同。從漢語特性來看，X版出現無訊息零代詞及不具分類意涵之含「的」的名詞組較Y 版多，可能會對閱讀X 版之讀者有較多閱讀理解之挑戰。從科學語言特性來看，Y版以具體事件逐漸抽象化的歷程來構作科學概念，符合技術建構歷程，並使用較多元的銜接關係 ...
葉佳承 Chia-Cheng Yeh +3 more
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The Theory of Relational Cohesion: Review of a Research Program [PDF]
, 2002 In this paper we analyze and review the theory of relational cohesion and attendant program of research. Since the early 1990s, the theory has evolved to answer a number of basic questions regarding cohesion and commitment in social exchange relations ...
Lawler, Edward J +2 more
core +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Frontiers in Political ScienceThis study investigates political efficacy—citizens’ beliefs in their ability to understand politics (internal political efficacy) and influence outcomes (external political efficacy)—in the context of town hall meeting (THMs) participation in a German ...
Yann P. M. Rees +4 more
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Mechanics of Sister Chromatids studied with a Polymer Model
Frontiers in Physics, 2013 Sister chromatid cohesion denotes the phenomenon that sister chromatids are initially attached to each other in mitosis to guarantee the error-free distribution into the daughter cells.
Yang eZhang +3 more
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Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte +13 more
wiley +1 more source
Understanding the Use of Cohesion Devices and Coherence in Writing [PDF]
, 2014 To make sense of the writing, the writer needs to understand the use of cohesion devices and coherence. It is important that writing be coherent as well as cohesive.
Siregar, S. (Syahreni)
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Remote Monitoring in Myasthenia Gravis: Exploring Symptom Variability
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Myasthenia gravis (MG) is a rare, autoimmune disorder characterized by fluctuating muscle weakness and potential life‐threatening crises. While continuous specialized care is essential, access barriers often delay timely interventions. To address this, we developed MyaLink, a telemedical platform for MG patients.
Maike Stein +13 more
wiley +1 more source