Results 51 to 60 of about 907,950 (295)

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Axiomatic Cohesion

open access: yesTheory and Applications of Categories, 2007
Summary: The nature of the spatial background for classical analysis and for modern theories of continuum physics requires more than the partial invariants of locales and cohomology rings for its description. As Maxwell emphasized, this description has various levels of precision depending on the needs of investigation.
openaire   +2 more sources

Fear of the Family. Barbara Lüthi in Conversation with Lauren Stokes

open access: yesÖsterreichische Zeitschrift für Geschichtswissenschaften
Talk with Lauren Stokes, historian at Northwestern University (Illinois), about her book "Fear of the Family, Guest Workers and Family Migration in the Federal Republic of Germany" (Oxford University Press 2022).
Barbara Lüthi, Lauren Stokes
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Encuesta sobre Conflicto y Cohesion Social en Chile 2014

open access: yes
The Survey on Conflict and Social Cohesion in Chile (ENACOES 2014) seeks to contribute to the understanding of beliefs, attitudes, and perceptions towards the different dimensions of coexistence and conflict present in Chilean ...
Reproducible Research, Centre for Social Conflict and Cohesion Studies COES
core   +1 more source

Mapping Social Cohesion Survey, 2007

open access: yes, 2018
The Social Cohesion Survey is a series of detailed surveys on social cohesion, immigration and population issues. A prime objective of the surveys is to further understanding of the social impact of Australia's increasingly diverse immigration program ...
Smith, Bruce
core   +1 more source

'Community cohesion' : reflections on a flawed paradigm [PDF]

open access: yes, 2012
This paper interrogates a concept at the core of a social policy agenda that has dominated thinking in the UK over the past decade. It argues that the notion of ‘community cohesion’ is based on a fundamentally flawed interpretation of the sources of ...
Ratcliffe, Peter
core   +1 more source

Navigating Conflicting Interests: The Role of Gender Competent Management for Effective Gender Equality Plans

open access: yesSocial Inclusion
The Horizon Europe mandate requiring Gender Equality Plans (GEPs) for funding eligibility has initiated a veritable wave of documented initiatives across research performing organisations (RPOs).
Angela Wroblewski, Karin Grasenick
doaj   +1 more source

Critical pedagogy and open data for educating towards social cohesion

open access: yesItalian Journal of Educational Technology, 2017
Reflections on the affordances of Open Data as Open Educational Resources for education towards social cohesion within a critical pedagogy discourse.
Annalisa Manca   +3 more
doaj   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

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