Results 151 to 160 of about 4,678,570 (340)
Molecular Oncology, EarlyView.C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald +18 more
wiley +1 more source
Cohort Profile: The Lausanne cohort 65+ (Lc65+) [PDF]
International Journal of Epidemiology, 2021 Yves Henchoz +7 more
openaire +3 more sources
Perinatal mortality by birth order within cohorts based on sibship size. [PDF]
, 1979 Leiv S. Bakketeig, Howard J. Hoffman
openalex +1 more source
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
Molecular Oncology, EarlyView.The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source
Modelling the cohort effect in CBD models using a piecewise linear approach [PDF]
, 2012 This paper discusses a new pattern of mortality model which is built on the form and knowledge of the two-factor mortality model named after its designers Cairns, Blake and Dowd (2006).
Sweeting, Paul, Zhao, Yiwei
core +1 more source
Cohort, age, and period effects upon the employment of white females: Evidence for 1957–1968 [PDF]
, 1977 George Farkas
openalex +1 more source
Molecular Oncology, EarlyView.TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach +8 more
wiley +1 more source
A cohort profile of the Graham Roberts study cohort
Frontiers in OncologyPurposeThe Graham Roberts Study was initiated in 2018 and is the first Trials Within Cohorts (TwiCs) study for bladder cancer. Its purpose is to provide an infrastructure for answering a breadth of research questions, including clinical, mechanistic, and supportive care centred questions for bladder cancer patients.ParticipantsAll consented patients ...
Beth Russell +19 more
openaire +3 more sources
Breast Cancer ResearchBackground Artificial intelligence (AI) algorithms for the independent assessment of screening mammograms have not been well established in a large screening cohort of Asian women.
Mi-ri Kwon +16 more
doaj +1 more source