Results 151 to 160 of about 6,267,604 (379)
PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer +21 morewiley +1 more sourceClinical impact of COVID-19 on patients with cancer (CCC19): a cohort study
The Lancet, 2020 N. Kuderer, T. Choueiri, D. Shah, Y. Shyr, S. Rubinstein, D. Rivera, S. Shete, Chih-Yuan Hsu, A. Desai, Gilberto Lopes, P. Grivas, P. Grivas, C. Painter, S. Peters, M. Thompson, Z. Bakouny, G. Batist, T. Bekaii-Saab, M. Bilen, N. Bouganim, M. B. Larroya, D. Castellano, S. Prete, D. Doroshow, P. Egan, A. Elkrief, D. Farmakiotis, D. Flora, M. Galsky, M. Glover, E. Griffiths, A. Gulati, Shilpa Gupta, Navid Hafez, T. Halfdanarson, J. Hawley, E. Hsu, A. Kasi, A. Khaki, A. Khaki, Christopher A. Lemmon, C. Lewis, Barbara B. Logan, T. Masters, R. McKay, R. Mesa, A. Morgans, M. Mulcahy, O. Panagiotou, P. Peddi, N. Pennell, K. Reynolds, Lane R. Rosen, R. Rosovsky, M. Salazar, A. Schmidt, Sumit A Shah, J. Shaya, J. Steinharter, K. Stockerl-Goldstein, S. Subbiah, D. Vinh, F. Wehbe, L. Weissmann, J. Wu, E. Wulff-Burchfield, Zhuoer Xie, Albert C. Yeh, Albert C. Yeh, P. Yu, A. Zhou, L. Zubiri, S. Mishra, G. Lyman, G. Lyman, B. Rini, J. Warner, M. Abidi, J. Acoba, Neeraj Agarwal, S. A. Ahmad, Archana Ajmera, Jessica Altman, Anne H. Angevine, Nilo Azad, Michael H. Bar, Aditya Bardia, Jill S. Barnholtz-Sloan, Briana Barrow, B. Bashir, Rimma Belenkaya, S. Berg, E. Bernicker, C. Bestvina, R. Bishnoi, Genevieve Marie Boland, Mark Bonnen, G. Bouchard, Daniel W. Bowles, F. Busser, A. Cabal, P. Caimi, Theresa M. Carducci, C. Casulo, James L. Chen, J. Clement, D. Chism, Erin Cook, C. Curran, Ahmad Daher, Mark Dailey, S. Dahiya, John Deeken, G. Demetri, Sandy DiLullo, N. Duma, Rawad Elias, B. Faller, L. Fecher, Lawrence E. Feldman, C. Friese, Paul Fu, Julie Fu, A. Futreal, J. Gainor, Jorge E Garcia, David M. Gill, E. Gillaspie, Antonio Giordano, Grace Glace, Axel Grothey, S. Gulati, M. Gurley, B. Halmos, Roy S. Herbst, D. Hershman, Kent Hoskins, R. Jain, Salma K. Jabbour, Alokkumar Jha, Douglas B. Johnson, Monika Joshi, K. Kelleher, J. Kharofa, H. Khan, J. Knoble, V. Koshkin, Amit A. Kulkarni, P. Lammers, J. Leighton, Mark A. Lewis, Xuanyi Li, Ang Li, K. M. Lo, A. Loaiza-Bonilla, Patricia LoRusso, C. Low, M. Lustberg, D. Mahadevan, Abdul-Hai Mansoor, Michelle Marcum, M. Markham, C. Marshall, Sandeep H. Mashru, Sara Matar, C. McNair, Shannon K. McWeeney, J. Mehnert, A. Menendez, H. Menon, M. Messmer, Ryan S. Monahan, Sarah Mushtaq, G. Nagaraj, Sarah Nagle, J. Naidoo, John M. Nakayama, Vikram M. Narayan, Heather H. Nelson, Eneida R. Nemecek, R. Nguyen, P. Nuzzo, P. Oberstein, A. Olszewski, Susie Owenby, M. Pasquinelli, John Philip, Sabitha Prabhakaran, M. Puc, Amelie G. Ramírez, J. Rathmann, S. Revankar, Young Soo Rho, Terence D. Rhodes, Robert L. Rice, Gregory Riely, J. Riess, Cameron Rink, E. Robilotti, Lori J Rosenstein, B. Routy, M. Rovito, M. W. Saif, Amit Sanyal, L. Schapira, C. Schwartz, Oscar K. Serrano, Mansi Shah, Chintan Shah, Grace Shaw, A. Shergill, Geoffrey P. Shouse, Heloisa P. Soares, Carmen C. Solorzano, Pramod K. Srivastava, Karen Stauffer, D. Stover, Jamie Stratton, Catherine Stratton, V. Subbiah, R. Tamimi, N. Tannir, U. Topaloglu, E. V. Allen, S. V. Loon, Karen Vega-Luna, N. Venepalli, Amit Verma, Praveen Vikas, Sarah Wall, P. L. Weinstein, Matthias Weiss, T. Wise-Draper, William A. Wood, Wenxin Xu, S. Yackzan, R. Zacks, Tian Zhang, Andrea J. Zimmer, Jack West +239 moresemanticscholar +1 more sourceCharacterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane +9 morewiley +1 more sourceCohort Profile: The Puberty Cohort in the Danish National Birth Cohort (DNBC) [PDF]
International Journal of Epidemiology, 2019 Jørn Olsen, Jørn Olsen, Andreas Ernst, Lea L B Lauridsen, Erik T. Parner, Ellen A. Nohr, Nis Brix, Anne-Marie Nybo Andersen, Bodil Hammer Bech, Inger Kristine Meder, Katrine Strandberg-Larsen, Cecilia Høst Ramlau-Hansen +11 moreopenaire +7 more sourcesAdenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski +14 morewiley +1 more sourceAccelerated increase in ferritin levels during menopausal transition as a marker of metabolic health
Scientific ReportsDespite ferritin’s role in iron and metabolic health, its timing and pattern of change relative to other iron biomarkers during the menopausal transition remain unclear, as blood loss shifts alter iron metabolism.Minjeong Kim, Yoosoo Chang, Yoosun Cho, Min-Jung Kwon, Hee-Kyung Joh, Ga-Young Lim, Ria Kwon, Jiin Ahn, Jungeun Park, Kye-Hyun Kim, Jae Keun Yoo, Seungho Ryu +11 moredoaj +1 more source
