Results 161 to 170 of about 3,608,670 (316)

Cohort profile: the Shanghai Birth Cohort [PDF]

open access: yesInternational Journal of Epidemiology, 2019
Jun Zhang   +30 more
openaire   +2 more sources

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Tempo-quantum and period-cohort interplay in fertility changes in Europe [PDF]

open access: yes
Using detailed data on period and cohort fertility in four European countries, this paper discusses various indicators of period fertility, including indicators adjusted for changes in fertility timing.
Tomas Sobotka
core  

Use of personal child health records in the UK: findings from the millennium cohort study. [PDF]

open access: yes, 2006
OBJECTIVES: The personal child health record (PCHR) is a record of a child's growth, development, and uptake of preventive health services, designed to enhance communication between parents and health professionals.
Bedford, H   +3 more
core  

A cohort profile of the Graham Roberts study cohort

open access: yesFrontiers in Oncology
PurposeThe Graham Roberts Study was initiated in 2018 and is the first Trials Within Cohorts (TwiCs) study for bladder cancer. Its purpose is to provide an infrastructure for answering a breadth of research questions, including clinical, mechanistic, and supportive care centred questions for bladder cancer patients.ParticipantsAll consented patients ...
Russell, Beth   +19 more
openaire   +4 more sources

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Longitudinal changes in mammographic density and reproductive hormones during the menopausal transition in middle-aged Korean women: effect modification by obesity

open access: yesBreast Cancer Research
Background Breast cancer, strongly associated with female hormones, peaks around perimenopause in Asia, versus post-menopause in Western countries. This study aims to investigate longitudinal changes in reproductive hormones and mammographic density (MD)
Yoosun Cho   +4 more
doaj   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

First birth trends in developed countries: a cohort analysis [PDF]

open access: yes
-cohort analysis, first ...
Jean-Paul Sardon, Tomas Frejka
core  

Cohort Profile: The Danish nurse cohort [PDF]

open access: yesInternational Journal of Epidemiology, 2011
Hundrup, Yrsa A   +3 more
openaire   +3 more sources

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