Results 101 to 110 of about 3,695,194 (322)

Systematic review of birth cohort studies in South East Asia and Eastern Mediterranean regions [PDF]

, 2011
Few longitudinal studies of children have taken place in the developing world, despite child mortality being concentrated there. This review summarises the methodologies and main outcomes of longitudinal studies of pre-school children (0 to 59 months) in
Campbell, Harry, McKinnon, Rachel
core   +2 more sources

Molecular subgroups of adult medulloblastoma: a long-term single-institution study [PDF]

, 2016
Background Recent transcriptomic approaches have demonstrated that there are at least 4 distinct subgroups in medulloblastoma (MB); however, survival studies of molecular subgroups in adult MB have been inconclusive because of small sample sizes. The aim
Ai, Lin, GIANGASPERO, FELICE, Li, Chunde, Li, Peng, Liu, Pinan, Luo, Lin, Ohgaki, Hiroko, Wang, Bo, Wang, Xingchao, Wang, Zhenmin, Xu, Lei, Yang, Zhijun, Zhang, Jing, Zhao, Fu   +13 more
core   +1 more source

Characterizing Parental Concerns About Lasting Impacts of Treatment in Children With B‐Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐acute lymphoblastic leukemia (B‐ALL) is the most common pediatric cancer, and while most children in high‐resource settings are cured, therapy carries risks for long‐term toxicities. Understanding parents’ concerns about these late effects is essential to guide anticipatory support and inform evolving therapeutic approaches ...
Kellee N. Parker, Sarah W. Alexander, Lisa M. Jacola, Kimberly A. Buff, Kyobin Hwang, Elham Hashemi, Gregory Stoddard, Lindsay A. Jibb   +7 more
wiley   +1 more source

The growth and development of cohort studies

Annals of Human Biology, 2020
Cohort studies are special forms of longitudinal studies that have long been accepted as the primary designs to acquire information on the interaction between the environment and health and the subsequent aetiology and progression of disease.
Noël Cameron
doaj   +1 more source

Predictors for elevation of Intraocular Pressure (IOP) on glaucoma patients; a retrospective cohort study design [PDF]

, 2022
Getasew Birhanu, Awoke Seyoum Tegegne
openalex   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Infantile Peanut Introduction and Peanut Allergy in Regions With a Low Prevalence of Peanut Allergy: The Japan Environment and Children’s Study (JECS)

Journal of Epidemiology
Background: In regions with a high prevalence of peanut allergy (PA), there is a consensus that the introduction of peanuts in early infancy is preventive against the development of PA.
Reiji Kojima, Ryoji Shinohara, Megumi Kushima, Hideki Yui, Sanae Otawa, Sayaka Horiuchi, Kunio Miyake, Hiroshi Yokomichi, Yuka Akiyama, Tadao Ooka, Zentaro Yamagata, the Japan Environment and Children’s Study Group   +11 more
doaj   +1 more source

The use of new technologies in Cohort studies [PDF]

Revista Brasileira em Promoção da Saúde, 2010
Existem relatos de trabalhos observacionais, longitudinais, desde século XVIII. Um dos primeiros trabalhos nesta linha consistiu no acompanhamento de filhos de pacientes tuberculosos por cerca de 20 anos(1).
Carlos Antonio Bruno da Silva, Querubina Bringel Olinda   +1 more
doaj  

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source