Results 101 to 110 of about 3,959,577 (361)

The Hertfordshire Cohort Study: an overview [PDF]

F1000Research, 2019
The Hertfordshire Cohort Study is a nationally unique study of men and women born in the English county of Hertfordshire in the early part of the 20th century. Records that detail their health in infancy and childhood have been preserved, their sociodemographic, lifestyle, medical and biological attributes have been characterised in later life, and ...
Cyrus Cooper, Cyrus Cooper, Sian M. Robinson, S. J. Simmonds, Sarah Carter, Elaine M. Dennison, Holly E. Syddall   +6 more
openaire   +4 more sources

NanoCMSer: a consensus molecular subtype stratification tool for fresh‐frozen and paraffin‐embedded colorectal cancer samples

Molecular Oncology, EarlyView.
Consensus molecular subtypes (CMS1‐4) have been identified to study colorectal cancer heterogeneity and serve as potential biomarkers. In this study, we developed and evaluated NanoCMSer, a NanoString‐based classifier using 55 genes, optimized for FF and FFPE to facilitate the clinical evaluation of CMS subtyping.
Arezo Torang, Simone van de Weerd, Veerle Lammers, Sander van Hooff, Inge van den Berg, Saskia van den Bergh, Miriam Koopman, Jan N. IJzermans, Jeanine M. L. Roodhart, Jan Koster, Jan Paul Medema   +10 more
wiley   +1 more source

Sex Differences in Birth Weight and Physical Activity in Japanese Schoolchildren

Journal of Epidemiology, 2018
Background: Lower birth weight (BW) is associated with increased chronic disease risk later in life. Previous studies suggest that this may be mediated principally via physical activity (PA). However, the association between BW and PA in children has not
Mitsuya Yamakita, Miri Sato, Kohta Suzuki, Daisuke Ando, Zentaro Yamagata   +4 more
doaj   +1 more source

Impact of molecular diagnostics and targeted cancer therapy on patient outcomes (MODIFY): a retrospective study of the implementation of precision oncology

Molecular Oncology, EarlyView.
The authors conducted a retrospective study of 94 patients with advanced cancer who underwent next‐generation sequencing (NGS) gene panel analysis and received targeted treatments when applicable. Results further support evidence indicating that molecular profiling provides clinical benefit.
Michaël Dang, Anna Schritz, Nikolai Goncharenko, Guy Berchem   +3 more
wiley   +1 more source

Sex-specific association between carbohydrate antigen 19–9 and incident type 2 diabetes

Scientific Reports
Carbohydrate antigen 19–9 (CA19-9) levels are associated with glycemic control, insulin resistance, and chronic complications in patients with type 2 diabetes (T2D). Women generally show higher CA19-9 levels despite a greater T2D prevalence in men.
Sujeong Shin, Yoosoo Chang, Seungho Ryu
doaj   +1 more source

Magnitude of problematic anger and its predictors in the Millennium Cohort

BMC Public Health, 2020
Background Problematic anger is intense anger associated with elevated generalized distress and that interferes with functioning. It also confers a heightened risk for the development of mental health problems.
Amy B. Adler, Cynthia A. LeardMann, Kimberly A. Roenfeldt, Isabel G. Jacobson, David Forbes, for the Millennium Cohort Study Team   +5 more
doaj   +1 more source

Skeletal muscle mass to visceral fat area ratio as a predictor of NAFLD in lean and overweight men and women with effect modification by sex

Hepatology Communications, 2022
The effect of sarcopenic visceral obesity on the risk of nonalcoholic fatty liver disease (NAFLD) is uncertain. We investigated (a) whether the skeletal muscle mass to visceral fat area ratio (SV ratio), as a measure of sarcopenic visceral obesity, is a ...
Yoosun Cho, Yoosoo Chang, Seungho Ryu, Hyun‐Suk Jung, Chan‐won Kim, Hyungseok Oh, Mi Kyung Kim, Won Sohn, Hocheol Shin, Sarah H. Wild, Christopher D. Byrne   +10 more
doaj   +1 more source

Risk of selection bias due to non-participation in a cohort study on pubertal timing. [PDF]

, 2020
BackgroundNon-participation in aetiologic studies of pubertal timing is frequent. However, little effort has been given to explore the risk and potential impact of selection bias in studies of pubertal timing.ObjectiveWe aimed to explore the risk of ...
Arah, Onyebuchi A, Brix, Nis, Ernst, Andreas, Henriksen, Tine Brink, Lauridsen, Lea Lykke Braskhøj, Olsen, Jørn, Parner, Erik Thorlund, Ramlau-Hansen, Cecilia Høst   +7 more
core  

Appetite suppressants and valvular heart disease - a systematic review [PDF]

, 2002
Background Although appetite suppressants have been implicated in the development of valvular heart disease, the exact level of risk is still uncertain.
AJ Burger, Angharad Pritchard-Copley, AP Fishman, BK Shively, CC Wee, CY Teramae, D Moher, DD Hensrud, EA Fisher, H Jick, H Jick, HM Connolly, JA Arnaiz, JG Jollis, JH Noseworthy, JM Gardin, K Metcalfe, MA Khan, MK Kancherla, NB Schiller, NE Lepor, NJ Weissman, NJ Weissman, NJ Weissman, RA Moore, Sheena Derry, ST Mast, TA Wadden, Yoon K Loke   +28 more
core   +2 more sources

Cohort Profile: The UK Women’s Cohort Study (UKWCS) [PDF]

International Journal of Epidemiology, 2015
Cohort Profile: The UK Women’s Cohort Study (UKWCS) Janet E Cade,* Victoria J Burley, Nisreen A Alwan, Jayne Hutchinson, Neil Hancock, Michelle A Morris, Diane E Threapleton and Darren C Greenwood School of Food Science and Nutrition, Leeds Institute for Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK, Department of Health ...
Cade, Janet E., Burley, Victoria J., Alwan, Nisreen A., Hutchinson, Jayne, Hancock, Neil, Morris, Michelle A., Threapleton, Diane E., Greenwood, Darren C.   +7 more
openaire   +5 more sources