Results 71 to 80 of about 43,381,677 (339)

Low-level alcohol consumption and cancer mortality

Scientific Reports, 2021
The effect of light-to-moderate alcohol consumption on cancer risk remains controversial. We examined the association between low-level alcohol consumption and cancer mortality. A cohort study included 331,984 Korean adults free of cancer at baseline who
Hyeonyoung Ko, Yoosoo Chang, Han-Na Kim, Jae-Heon Kang, Hocheol Shin, Eunju Sung, Seungho Ryu   +6 more
doaj   +1 more source

Musculoskeletal conditions may increase the risk of chronic disease: a systematic review and meta-analysis of cohort studies

BMC Medicine, 2018
BackgroundChronic diseases and musculoskeletal conditions have a significant global burden and frequently co-occur. Musculoskeletal conditions may contribute to the development of chronic disease; however, this has not been systematically synthesised. We
A. Williams, S. Kamper, J. Wiggers, Kate M. O’Brien, Hopin Lee, L. Wolfenden, S. Yoong, E. Robson, J. McAuley, J. Hartvigsen, C. Williams   +10 more
semanticscholar   +1 more source

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

Molecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane, Jérôme Ambroise, Cédric van Marcke, Mieke Van Bockstal, Martine Berlière, Christine Galant, Hélène Dano, Médina Lougué, Elena Benidovskaya, Guy Jerusalem, Vincent Bours, Claire Josse, Jérôme Thiry, Aurélie Daumerie, Caroline Bouzin, Cyril Corbet, François P. Duhoux   +16 more
wiley   +1 more source

Cohort Profile: Shahroud Eye Cohort Study [PDF]

International Journal of Epidemiology, 2012
The Shahroud Eye Cohort Study was set up to determine the prevalence and incidence of visual impairment and major eye conditions in the 40-64-year-old population of Shahroud as a Middle Eastern population. The first phase of the study was conducted in 2009-10.
Hassan Koohian, Mohammad Reza Khademi, Mehdi Mirzaii, Ebrahim Jafarzadehpur, Mohammad Shariati, Ahmad Kheirkhah, Mehdi Khabazkhoob, Kamran Hodjatjalali, Sarvenaz Malihi, Kamran Yazdani, Reza Chaman, Akbar Fotouhi, Hassan Hashemi, Mohammad Hassan Emamian   +13 more
openaire   +3 more sources

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

Long‐Term Particulate Matter Exposure and Incidence of Arrhythmias: A Cohort Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Studies have shown that short‐term exposure to air pollution is associated with cardiac arrhythmia hospitalization and mortality. However, the relationship between long‐term particulate matter air pollution and arrhythmias is still unclear. We
Zhenyu Zhang, Jeonggyu Kang, Yun Soo Hong, Yoosoo Chang, Seungho Ryu, Jihwan Park, Juhee Cho, Eliseo Guallar, Ho Cheol Shin, Di Zhao   +9 more
doaj   +1 more source

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi, Eric Feng, Nicholas R. Rydzewski, Amy K. Taylor, Jamie M. Sperger, Yue Shi, Kyle T. Helzer, Matthew L. Bootsma, Viridiana Carreno, Alex H. Chang, Luke A. Nunamaker, Grace C. Blitzer, Tianfu Andy Shang, Aishwarya Subramanian, Anders Bjartell, Andreas Josefsson, Pernilla Wikström, Emily Feng, Manish Kohli, Rendong Yang, Scott M. Dehm, Eric J. Small, Rahul Aggarwal, David A. Quigley, Joshua M. Lang, Shuang G. Zhao, Martin Sjöström   +26 more
wiley   +1 more source

Early life vitamin D status and asthma and wheeze: a systematic review and meta-analysis

BMC Pulmonary Medicine, 2018
Background Vitamin D deficiency has been linked to an increased risk of asthma. This study aimed to quantify the effect of early life vitamin D status on asthma and wheeze later in life.
Song-Ying Shen, Wan-Qing Xiao, Jin-Hua Lu, Ming-Yang Yuan, Jian-Rong He, Hui-Min Xia, Xiu Qiu, Kar Keung Cheng, Kin Bong Hubert Lam   +8 more
doaj   +1 more source

Cohort Profile: Cohort Hip and Cohort Knee (CHECK) study [PDF]

International Journal of Epidemiology, 2014
The Cohort Hip and Cohort Knee (CHECK) study included participants with early symptomatic osteoarthritis (OA) of the hip or knee and evaluated clinical, radiographic and biochemical variables in order to establish the course, prognosis and underlying mechanisms of early symptomatic osteoarthritis.
Wesseling, J., Boers, Maarten, Viergever, Max A, Hilberdink, Wim Kha, Lafeber, Floris Pjg, Dekker, Joost, Bijlsma, Johannes Wj   +6 more
openaire   +4 more sources

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

Molecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé, Lisa Hahnefeld, Katharina J. Wenger, Donat Kögel, Joachim Steinbach, Gerd Geisslinger, Michael W. Ronellenfitsch, Irmgard Tegeder   +7 more
wiley   +1 more source