Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals [PDF]
A large-scale GWAS provides insight on diabetes-dependent genetic effects on the glomerular filtration rate, a common metric to monitor kidney health in disease. Reduced glomerular filtration rate (GFR) can progress to kidney failure.
DiscovEHR MyCode Study+11 more
core +4 more sources
Use of personal child health records in the UK: findings from the millennium cohort study. [PDF]
OBJECTIVES: The personal child health record (PCHR) is a record of a child's growth, development, and uptake of preventive health services, designed to enhance communication between parents and health professionals.
Bedford, H+3 more
core +1 more source
External validation of the PAGE-B score for HCC risk prediction in people living with HIV/HBV coinfection [PDF]
BACKGROUND & AIMS: HBV coinfection is common among people living with HIV (PLWH) and is the most important cause of hepatocellular carcinoma (HCC). While risk prediction tools for HCC have been validated in patients with HBV monoinfection, they have not ...
ANRS CO3 Aquitaine Cohort+3 more
core
Prevalence and risk factors related to haloperidol use for delirium in adult intensive care patients : the multinational AID-ICU inception cohort study [PDF]
We assessed the prevalence and variables associated with haloperidol use for delirium in ICU patients and explored any associations of haloperidol use with 90-day mortality. All acutely admitted, adult ICU patients were screened during a 2-week inception
AID-ICU Cohort Study Co-authors+1 more
core +1 more source
Multi-ancestry genome-wide association study accounting for gene-psychosocial factor interactions identifies novel loci for blood pressure traits [PDF]
Publisher Copyright: © 2020 The Author(s)Psychological and social factors are known to influence blood pressure (BP) and risk of hypertension and associated cardiovascular diseases.
Kilpeläinen, Tuomas O.+4 more
core +1 more source
Trajectories of body mass index and waist circumference in four Peruvian settings at different level of urbanisation: the CRONICAS Cohort Study [PDF]
BACKGROUND: Studies have reported the incidence/risk of becoming obese, but few have described the trajectories of body mass index (BMI) and waist circumference (WC) over time, especially in low/middle-income countries.
Bernabé-Ortiz, A+6 more
core +2 more sources
Inability to get up after falling, subsequent time on floor, and summoning help: prospective cohort study in people over 90. [PDF]
OBJECTIVES: To describe the incidence and extent of lying on the floor for a long time after being unable to get up from a fall among people aged over 90; to explore their use of call alarm systems in these circumstances.
Brayne, Carol+2 more
core +1 more source
The impact of maternal employment on breast-feeding duration in the UK Millennium Cohort Study [PDF]
OBJECTIVE: To examine the relationship of maternal employment characteristics, day care arrangements and the type of maternity leave pay to breast-feeding for at least 4 months. DESIGN: Cohort study. SETTING: Babies aged 9 months in the Millennium Cohort
Dezateux, C+4 more
core +1 more source
Employment 12 months after kidney transplantation: an in-depth bio-psycho-social analysis of the Swiss Transplant Cohort [PDF]
Return to work with or after a chronic disease is a dynamic process influenced by a variety of interactions between personal, work, societal and medical resources or constraints.
Danuser, Brigitta+5 more
core +8 more sources
Falls in advanced old age: recalled falls and prospective follow-up of over-90-year-olds in the Cambridge City over-75s Cohort study. [PDF]
BACKGROUND: The "oldest old" are now the fastest growing section of most western populations, yet there are scarcely any data concerning even the common problem of falls amongst the very old. Prospective data collection is encouraged as the most reliable
Brayne, Carol+3 more
core +1 more source