Results 111 to 120 of about 45,688,233 (408)

Sleep and nighttime energy consumption in early childhood: a population‐based cohort study

Pediatric obesity, 2015
Shorter sleep is a risk factor for weight gain in young children. Experimental studies show that sleep deprivation is associated with higher nighttime energy intake, but no studies have examined the patterning of energy intake in relation to nighttime ...
L. McDonald, Jane Wardle, Clare H. Llewellyn, Laura Johnson, C. V. Jaarsveld, H. Syrad, Abigail Fisher   +6 more
semanticscholar   +1 more source

Mortality in patients with successful initial response to highly active antiretroviral therapy is still higher than in non-HIV-infected individuals.

, 2005
Mortality in HIV-infected patients has decreased dramatically since the introduction of highly active antiretroviral therapy (HAART). We analyzed progression to death in a population of 3678 antiretroviral treatment-naive patients from the ATHENA ...
Anderson, Roy M, ATHENA National Observational Cohort Study, Danner, Sven, de Wolf, Frank, Ghani, Azra C, Gras, Luuk, van Sighem, Ard   +6 more
core   +2 more sources

Integrative systems‐level analysis reveals a contextual crosstalk between hypoxia and global metabolism in human breast tumors

Molecular Oncology, EarlyView.
Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam, Salem Chouaib, Mohammad Askandar Iqbal   +2 more
wiley   +1 more source

Maternal Pregnancy-Related Anxiety Is Associated With Sexually Dimorphic Alterations in Amygdala Volume in 4-Year-Old Children

Frontiers in Behavioral Neuroscience, 2019
Prenatal stress is associated with child behavioral outcomes increasing susceptibility for psychiatric disorders in later life. Altered fetal brain development might partly mediate this association, as some studies suggest.
Henriette Acosta, Jetro J. Tuulari, Jetro J. Tuulari, Jetro J. Tuulari, Noora M. Scheinin, Niloofar Hashempour, Olli Rajasilta, Tuomas I. Lavonius, Juho Pelto, Virva Saunavaara, Riitta Parkkola, Tuire Lähdesmäki, Linnea Karlsson, Linnea Karlsson, Hasse Karlsson, Hasse Karlsson   +15 more
doaj   +1 more source

Prevalence and Risk Factors of Incidental Findings in Brain MRIs of Healthy Neonates—The FinnBrain Birth Cohort Study

Frontiers in Neurology, 2020
Background: Birth is a traumatic event with molding forces directed to the fetal skull, which may result in intracranial hemorrhages. However, the knowledge on prevalence and risk factors of incidental brain magnetic resonance imaging (MRI) findings in ...
Venla Kumpulainen, Satu J. Lehtola, Jetro J. Tuulari, Jetro J. Tuulari, Eero Silver, Anni Copeland, Riikka Korja, Riikka Korja, Hasse Karlsson, Hasse Karlsson, Hasse Karlsson, Linnea Karlsson, Linnea Karlsson, Linnea Karlsson, Harri Merisaari, Harri Merisaari, Harri Merisaari, Riitta Parkkola, Riitta Parkkola, Jani Saunavaara, Tuire Lähdesmäki, Tuire Lähdesmäki, Noora M. Scheinin, Noora M. Scheinin   +23 more
doaj   +1 more source

Factors influencing treatment status of syphilis among pregnant women: a retrospective cohort study in Guangzhou, China

International Journal for Equity in Health, 2023
Background Many syphilis infected pregnant women do not receive treatment, representing a major missed opportunity to reduce the risk of syphilis-related adverse pregnancy outcomes.
Huihui Liu, Niannian Chen, Weiming Tang, Songying Shen, Jia Yu, Huiyun Xiao, Xingwen Zou, Jianrong He, Joseph D. Tucker, Xiu Qiu   +9 more
doaj   +1 more source

Cohort Profile: Cohort Hip and Cohort Knee (CHECK) study [PDF]

International Journal of Epidemiology, 2014
The Cohort Hip and Cohort Knee (CHECK) study included participants with early symptomatic osteoarthritis (OA) of the hip or knee and evaluated clinical, radiographic and biochemical variables in order to establish the course, prognosis and underlying mechanisms of early symptomatic osteoarthritis.
Wesseling, J., Boers, Maarten, Viergever, Max A, Hilberdink, Wim Kha, Lafeber, Floris Pjg, Dekker, Joost, Bijlsma, Johannes Wj   +6 more
openaire   +4 more sources

MUCE: Bayesian Hierarchical Modeling for the Design and Analysis of Phase 1b Multiple Expansion Cohort Trials [PDF]

, 2020
We propose a multiple cohort expansion (MUCE) approach as a design or analysis method for phase 1b multiple expansion cohort trials, which are novel first-in-human studies conducted following phase 1a dose escalation. The MUCE design is based on a class of Bayesian hierarchical models that adaptively borrow information across arms.
arxiv   +1 more source

Development and validation of QRISK3 risk prediction algorithms to estimate future risk of cardiovascular disease: prospective cohort study

British medical journal, 2017
Objectives To develop and validate updated QRISK3 prediction algorithms to estimate the 10 year risk of cardiovascular disease in women and men accounting for potential new risk factors. Design Prospective open cohort study.
J. Hippisley-Cox, C. Coupland, P. Brindle   +2 more
semanticscholar   +1 more source

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

Molecular Oncology, EarlyView.
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou, Argyro Roumeliotou, Evangelia Pantazaka, Athanasios‐Nasir Shaukat, Athina Christopoulou, Angelos Koutras, Foteinos‐Ioannis Dimitrakopoulos, Vassilis Georgoulias, Anastasia Xagara, Evangelia Chantzara, Fillipos Koinis, Athanasios Kotsakis, Constantinos Stathopoulos, Galatea Kallergi   +13 more
wiley   +1 more source