Results 131 to 140 of about 45,688,233 (408)

The Hertfordshire Cohort Study: an overview [PDF]

open access: yesF1000Research, 2019
The Hertfordshire Cohort Study is a nationally unique study of men and women born in the English county of Hertfordshire in the early part of the 20th century. Records that detail their health in infancy and childhood have been preserved, their sociodemographic, lifestyle, medical and biological attributes have been characterised in later life, and ...
Cyrus Cooper   +6 more
openaire   +4 more sources

Integration of single‐cell and bulk RNA‐sequencing data reveals the prognostic potential of epithelial gene markers for prostate cancer

open access: yesMolecular Oncology, EarlyView.
Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley   +1 more source

Prospective Epidemiological Research Studies in Iran (the PERSIAN Cohort Study): Rationale, Objectives, and Design.

open access: yesAmerican Journal of Epidemiology, 2018
Noncommunicable diseases (NCDs) account for 76% of deaths in Iran, and this number is on the rise, in parallel with global rates. Many risk factors associated with NCDs are preventable; however, it is first necessary to conduct observational studies to ...
H. Poustchi   +27 more
semanticscholar   +1 more source

Late presentation for hepatitis C treatment: prevalence and risk factors in the Swiss Hepatitis C Cohort [PDF]

open access: yes
OBJECTIVE Patients with 'late presentation' (LP) of chronic hepatitis C infection (HCV) have already developed advanced liver disease before receiving direct-acting antiviral (DAA) treatment.
Bruggmann, Philip   +3 more
core   +1 more source

Social capital and health in a national cohort of 82,482 Open University adults in Thailand [PDF]

open access: yes, 2011
We report associations between social capital and health among 82,482 adults in a national cohort of Open University students residing throughout Thailand.
Khamman, Suwanee   +5 more
core   +2 more sources

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

open access: yesMolecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin   +14 more
wiley   +1 more source

Cohort Profile: The UK Women’s Cohort Study (UKWCS) [PDF]

open access: yesInternational Journal of Epidemiology, 2015
Cohort Profile: The UK Women’s Cohort Study (UKWCS) Janet E Cade,* Victoria J Burley, Nisreen A Alwan, Jayne Hutchinson, Neil Hancock, Michelle A Morris, Diane E Threapleton and Darren C Greenwood School of Food Science and Nutrition, Leeds Institute for Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK, Department of Health ...
Cade, Janet E.   +7 more
openaire   +5 more sources

Association of antiviral prophylaxis and rituximab use with posttransplant lymphoproliferative disorders (PTLDs): A nationwide cohort study

open access: yesAmerican Journal of Transplantation, 2020
Posttransplant lymphoproliferative disorder (PTLD) is a serious complication of solid organ transplantation (SOT). Most PTLD cases are associated with Epstein–Barr virus (EBV) infection.
L. Walti   +14 more
semanticscholar   +1 more source

Development and validation of a risk score for chronic kidney disease in HIV infection using prospective cohort data from the D:A:D study. [PDF]

open access: yes, 2015
Chronic kidney disease (CKD) is a major health issue for HIV-positive individuals, associated with increased morbidity and mortality. Development and implementation of a risk score model for CKD would allow comparison of the risks and benefits of adding ...
D:A:D study group, .   +18 more
core  

Analysis of comprehensive genomic profiling of solid tumors with a novel assay for broad analysis in clinical diagnostics

open access: yesMolecular Oncology, EarlyView.
In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen   +17 more
wiley   +1 more source

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