Results 51 to 60 of about 45,688,233 (408)

Prevalence of congenital microcephaly and its risk factors in an area at risk of Zika outbreaks

open access: yesBMC Pregnancy and Childbirth, 2021
Background Prevalence of neonatal microcephaly in populations without Zika-epidemics is sparse. The study aimed to report baseline prevalence of congenital microcephaly and its relationship with prenatal factors in an area at risk of Zika outbreak ...
Songying Shen   +12 more
doaj   +1 more source

COVID-19 in solid organ transplant: A multi-center cohort study

open access: yesClinical Infectious Diseases, 2020
Background The COVID-19 pandemic has led to significant reductions in transplantation, motivated in part by concerns of disproportionately more severe disease among solid organ transplant (SOT) recipients.
O. Kates   +33 more
semanticscholar   +1 more source

Incremental predictive value of platelet parameters for preeclampsia: results from a large prospective cohort study

open access: yesBMC Pregnancy and Childbirth, 2023
Background Platelet parameters during pregnancy were associated with the risk of preeclampsia (PE), but the predictive value of these parameters for PE remained unclear.
Shan-Shan Lin   +8 more
doaj   +1 more source

Cohort Profile Update: Lifelines, a three-generation cohort study and biobank

open access: yesInternational Journal of Epidemiology, 2021
Cohort Profile Update: Lifelines, a threegeneration cohort study and biobank Anna Sijtsma,* Johanna Rienks , Pim van der Harst, Gerjan Navis, Judith GM Rosmalen and Aafje Dotinga Lifelines Cohort Study, Roden, The Netherlands, Department of Cardiology ...
A. Sijtsma   +5 more
semanticscholar   +1 more source

Improving estimation efficiency of case-cohort study with interval-censored failure time data [PDF]

open access: yesarXiv, 2023
The case-cohort design is a commonly used cost-effective sampling strategy for large cohort studies, where some covariates are expensive to measure or obtain. In this paper, we consider regression analysis under a case-cohort study with interval-censored failure time data, where the failure time is only known to fall within an interval instead of being
arxiv  

Adaptive Cohort Size Determination Method for Bayesian Optimal Interval Phase I/II Design to Shorten Clinical Trial Duration [PDF]

open access: yesarXiv, 2023
Recently, the strategy for dose optimization in oncology has shifted to conduct Phase 2 randomized controlled trials with multiple doses. Optimal biologic dose selection from Phase 1 trial data to determine candidate doses for Phase 2 trials has been gaining attention.
arxiv  

Parental divorce in childhood does not independently predict maternal depressive symptoms during pregnancy

open access: yesBMC Pregnancy and Childbirth, 2020
Background This study sought to investigate if parental divorce in childhood increases the risk for depressive symptoms in pregnancy. Methods Women were recruited during their ultrasound screening in gestational week (gwk) 12.
Elviira Porthan   +6 more
doaj   +1 more source

Distinct H3K27me3 and H3K27ac Modifications in Neural Tube Defects Induced by Benzo[a]pyrene

open access: yesBrain Sciences, 2023
The pathological mechanisms of neural tube defects (NTDs) are not yet fully understood. Although the dysregulation of histone modification in NTDs is recognized, it remains to be fully elucidated on a genome-wide level.
Shanshan Lin   +3 more
doaj   +1 more source

Epidemiological and cohort study finds no association between COVID-19 and Guillain-Barré syndrome

open access: yesmedRxiv, 2020
Background Reports of Guillain-Barre Syndrome (GBS) have emerged during the Coronavirus Disease 2019 (COVID-19) pandemic. This epidemiological and cohort study sought to investigate any causative association between COVID-19 infection and GBS.
S. Keddie   +41 more
semanticscholar   +1 more source

Maternal pre-pregnancy body mass index is associated with newborn offspring hypothalamic mean diffusivity: a prospective dual-cohort study

open access: yesBMC Medicine, 2023
Background An extensive body of animal literature supports the premise that maternal obesity during pregnancy can alter the development of the fetal hypothalamus (HTH, a critical regulator of energy balance) with implications for offspring obesity risk ...
Jerod M. Rasmussen   +10 more
doaj   +1 more source

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